ENSG00000108592


Homo sapiens

Features
Gene ID: ENSG00000108592
  
Biological name :FTSJ3
  
Synonyms : FTSJ3 / FtsJ RNA methyltransferase homolog 3 / Q8IY81
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q23.3
Gene start: 63819433
Gene end: 63830012
  
Corresponding Affymetrix probe sets: 218103_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000462290
Ensembl peptide - ENSP00000462342
Ensembl peptide - ENSP00000463229
Ensembl peptide - ENSP00000463980
Ensembl peptide - ENSP00000464361
Ensembl peptide - ENSP00000464648
Ensembl peptide - ENSP00000396673
Ensembl peptide - ENSP00000462212
NCBI entrez gene - 117246     See in Manteia.
RefSeq - NM_017647
RefSeq Peptide - NP_060117
swissprot - Q8IY81
swissprot - J3KRY4
swissprot - J3KS36
swissprot - J3KS74
swissprot - J3QKT6
swissprot - J3QR05
swissprot - J3QRS5
swissprot - J3QSE2
Ensembl - ENSG00000108592
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ftsj3ENSDARG00000104938Danio rerio
 FTSJ3ENSGALG00000032993Gallus gallus
 Ftsj3ENSMUSG00000020706Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002877  Ribosomal RNA methyltransferase FtsJ domain
 IPR011989  Armadillo-like helical
 IPR012920  Ribosomal RNA methyltransferase, Spb1, C-terminal
 IPR015507  Ribosomal RNA large subunit methyltransferase E
 IPR024576  Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381
 IPR028589  AdoMet-dependent rRNA methyltransferase, Spb1
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0001510 RNA methylation IEA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0031167 rRNA methylation IBA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0042254 ribosome biogenesis IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0030687 preribosome, large subunit precursor IBA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008649 rRNA methyltransferase activity IEA
 molecular_functionGO:0008650 rRNA (uridine-2"-O-)-methyltransferase activity IBA
 molecular_functionGO:0016435 rRNA (guanine) methyltransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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