ENSG00000109118


Homo sapiens

Features
Gene ID: ENSG00000109118
  
Biological name :PHF12
  
Synonyms : PHD finger protein 12 / PHF12 / Q96QT6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q11.2
Gene start: 28905250
Gene end: 28951771
  
Corresponding Affymetrix probe sets: 231815_at (Human Genome U133 Plus 2.0 Array)   234939_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467921
Ensembl peptide - ENSP00000468478
Ensembl peptide - ENSP00000268756
Ensembl peptide - ENSP00000329933
Ensembl peptide - ENSP00000368157
Ensembl peptide - ENSP00000463900
Ensembl peptide - ENSP00000465017
Ensembl peptide - ENSP00000465161
Ensembl peptide - ENSP00000465255
Ensembl peptide - ENSP00000465374
Ensembl peptide - ENSP00000466695
Ensembl peptide - ENSP00000467091
Ensembl peptide - ENSP00000467363
NCBI entrez gene - 57649     See in Manteia.
RefSeq - XM_017024904
RefSeq - NM_001033561
RefSeq - NM_001290131
RefSeq - NM_020889
RefSeq - XM_005258015
RefSeq - XM_005258016
RefSeq - XM_011525078
RefSeq - XM_011525079
RefSeq - XM_011525082
RefSeq - XM_011525083
RefSeq - XM_017024903
RefSeq Peptide - NP_001277060
RefSeq Peptide - NP_001028733
RefSeq Peptide - NP_065940
swissprot - K7EJ43
swissprot - K7EJN7
swissprot - Q96QT6
swissprot - K7EMX6
swissprot - K7ENU0
swissprot - K7EPF7
swissprot - K7EQP5
swissprot - K7ERZ4
swissprot - K7EJY3
swissprot - C9J9G2
swissprot - J3QQU3
Ensembl - ENSG00000109118
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phf12aENSDARG00000074303Danio rerio
 phf12bENSDARG00000075509Danio rerio
 PHF12ENSGALG00000031368Gallus gallus
 Phf12ENSMUSG00000037791Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AIRE / O43918 / autoimmune regulatorENSG000001602249


Protein motifs (from Interpro)
Interpro ID Name
 IPR000253  Forkhead-associated (FHA) domain
 IPR001965  Zinc finger, PHD-type
 IPR008984  SMAD/FHA domain superfamily
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR031966  PHD finger protein 12, MRG binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0016580 Sin3 complex IDA
 cellular_componentGO:0017053 transcriptional repressor complex IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0001222 transcription corepressor binding IEA
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035091 phosphatidylinositol binding IDA
 molecular_functionGO:0042393 histone binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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