ENSG00000113532


Homo sapiens

Features
Gene ID: ENSG00000113532
  
Biological name :ST8SIA4
  
Synonyms : Q92187 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 / ST8SIA4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q21.1
Gene start: 100806935
Gene end: 100903266
  
Corresponding Affymetrix probe sets: 1554460_at (Human Genome U133 Plus 2.0 Array)   206925_at (Human Genome U133 Plus 2.0 Array)   230261_at (Human Genome U133 Plus 2.0 Array)   230836_at (Human Genome U133 Plus 2.0 Array)   242943_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000428914
Ensembl peptide - ENSP00000231461
Ensembl peptide - ENSP00000428826
NCBI entrez gene - 7903     See in Manteia.
OMIM - 602547
RefSeq - XM_011543630
RefSeq - NM_005668
RefSeq - NM_175052
RefSeq - XM_005272078
RefSeq Peptide - NP_778222
RefSeq Peptide - NP_005659
swissprot - Q92187
swissprot - E5RFK3
Ensembl - ENSG00000113532
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 st8sia4ENSDARG00000103600Danio rerio
 ST8SIA4ENSGALG00000026192Gallus gallus
 Q64692ENSMUSG00000040710Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q92186 / ST8SIA2 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2ENSG0000014055758
O43173 / ST8SIA3 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3ENSG0000017751132
O15466 / ST8SIA5 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5ENSG0000010163829
Q92185 / ST8SIA1 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1ENSG0000011172826
P61647 / ST8SIA6 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6ENSG0000014848826


Protein motifs (from Interpro)
Interpro ID Name
 IPR001675  Glycosyl transferase family 29
 IPR012163  Sialyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001574 ganglioside biosynthetic process IDA
 biological_processGO:0006464 cellular protein modification process TAS
 biological_processGO:0006486 protein glycosylation IDA
 biological_processGO:0006491 N-glycan processing IDA
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0009311 oligosaccharide metabolic process IDA
 biological_processGO:0097503 sialylation IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IDA
 molecular_functionGO:0008373 sialyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0033691 sialic acid binding IC


Pathways (from Reactome)
Pathway description
Sialic acid metabolism
NCAM1 interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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