ENSG00000177511


Homo sapiens

Features
Gene ID: ENSG00000177511
  
Biological name :ST8SIA3
  
Synonyms : O43173 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 / ST8SIA3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q21.31
Gene start: 57350813
Gene end: 57371731
  
Corresponding Affymetrix probe sets: 208064_s_at (Human Genome U133 Plus 2.0 Array)   208065_at (Human Genome U133 Plus 2.0 Array)   230262_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000320431
Ensembl peptide - ENSP00000467752
NCBI entrez gene - 51046     See in Manteia.
OMIM - 609478
RefSeq - NM_015879
RefSeq Peptide - NP_056963
swissprot - O43173
swissprot - K7EQB3
Ensembl - ENSG00000177511
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 st8sia3ENSDARG00000045301Danio rerio
 ENSGALG00000026991Gallus gallus
 ST8SIA3ZENSGALG00000039151Gallus gallus
 Q64689ENSMUSG00000056812Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q92186 / ST8SIA2 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2ENSG0000014055733
P61647 / ST8SIA6 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6ENSG0000014848831
Q92187 / ST8SIA4 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4ENSG0000011353230
Q92185 / ST8SIA1 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1ENSG0000011172828
O15466 / ST8SIA5 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5ENSG0000010163825


Protein motifs (from Interpro)
Interpro ID Name
 IPR001675  Glycosyl transferase family 29
 IPR012163  Sialyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001574 ganglioside biosynthetic process IDA
 biological_processGO:0006486 protein glycosylation IDA
 biological_processGO:0006491 N-glycan processing IDA
 biological_processGO:0006688 glycosphingolipid biosynthetic process TAS
 biological_processGO:0009100 glycoprotein metabolic process IDA
 biological_processGO:0009311 oligosaccharide metabolic process IDA
 biological_processGO:0097503 sialylation IEA
 biological_processGO:1990743 protein sialylation IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IDA
 molecular_functionGO:0008373 sialyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0033691 sialic acid binding IC
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Sialic acid metabolism
N-Glycan antennae elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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