ENSDARG00000045301


Danio rerio

Features
Gene ID: ENSDARG00000045301
  
Biological name :st8sia3
  
Synonyms : ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 / st8sia3
  
Possible biological names infered from orthology : O43173 / Q64689 / Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 1780790
Gene end: 1799265
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000066622
NCBI entrez gene - 553510     See in Manteia.
RefSeq - NM_001113432
RefSeq Peptide - NP_001106903
swissprot - B0CN48
ZFIN ID - ZDB-GENE-060228-4
Ensembl - ENSDARG00000045301
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000026991Gallus gallus
 ST8SIA3ZENSGALG00000039151Gallus gallus
 O43173ENSG00000177511Homo sapiens
 Q64689ENSMUSG00000056812Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
st8sia2 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 / O35696* / Q92186* / Alpha-2,8-sialyltransferase 8B *ENSDARG0000001878831
st8sia4 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 / Q92187*ENSDARG0000010360029
st8sia6 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6ENSDARG0000002119528
st8sia7.1 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 7.1ENSDARG0000005421127
st8sia5 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 / O15466* / P70126* / Alpha-2,8-sialyltransferase 8E *ENSDARG0000003658426
st8sia1 / ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 / Q64687* / Q92185* / Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase *ENSDARG0000009822126


Protein motifs (from Interpro)
Interpro ID Name
 IPR001675  Glycosyl transferase family 29
 IPR012163  Sialyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0007517 muscle organ development IMP
 biological_processGO:0046716 muscle cell cellular homeostasis IMP
 biological_processGO:0097503 sialylation IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity ISS
 molecular_functionGO:0008373 sialyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
Sialic acid metabolism
N-Glycan antennae elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye agenesis , abnormal
Show

 ZFA:0000109 forebrain forebrain agenesis , abnormal
Show

 ZFA:0000128 midbrain midbrain agenesis , abnormal
Show

 ZFA:0000610 vertical myoseptum vertical myoseptum obtuse angle to vertical myoseptum , abnormal
Show

 ZFA:0001056 myotome myotome decreased length , abnormal
myotome myofibril disorganized , abnormal
Show

 ZFA:0001117 post-vent region post-vent region morphology , abnormal
Show

 ZFA:0009052 motor neuron motor neuron spatial pattern , abnormal
motor neuron defasciculated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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