ENSG00000116147


Homo sapiens

Features
Gene ID: ENSG00000116147
  
Biological name :TNR
  
Synonyms : Q92752 / tenascin R / TNR
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q25.1
Gene start: 175315194
Gene end: 175743770
  
Corresponding Affymetrix probe sets: 1564897_at (Human Genome U133 Plus 2.0 Array)   206990_at (Human Genome U133 Plus 2.0 Array)   213841_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000263525
Ensembl peptide - ENSP00000356646
Ensembl peptide - ENSP00000403413
NCBI entrez gene - 7143     See in Manteia.
OMIM - 601995
RefSeq - XM_017002219
RefSeq - NM_003285
RefSeq - XM_011509949
RefSeq - XM_017002218
RefSeq Peptide - NP_003276
swissprot - H0Y668
swissprot - Q92752
Ensembl - ENSG00000116147
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnrENSDARG00000020771Danio rerio
 TNRENSGALG00000004526Gallus gallus
 TnrENSMUSG00000015829Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNC / P24821 / tenascin CENSG0000004198245
TNN / Q9UQP3 / tenascin NENSG0000012033234
FN1 / P02751 / fibronectin 1ENSG0000011541423
TNXB / P22105 / tenascin XBENSG0000016847716
FGA / P02671 / fibrinogen alpha chainENSG0000017156012
FGB / P02675 / fibrinogen beta chainENSG000001715649
FGL1 / Q08830 / fibrinogen like 1ENSG000001047608
Q9Y5C1 / ANGPTL3 / angiopoietin like 3ENSG000001328558
FGG / P02679 / fibrinogen gamma chainENSG000001715578
Q86XS5 / ANGPTL5 / angiopoietin like 5ENSG000001871518
Q9BY76 / ANGPTL4 / angiopoietin like 4ENSG000001677727


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR002181  Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
 IPR003961  Fibronectin type III
 IPR013032  EGF-like, conserved site
 IPR013111  EGF-like domain, extracellular
 IPR013783  Immunoglobulin-like fold
 IPR014715  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2
 IPR014716  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
 IPR033079  Tenascin-R
 IPR036056  Fibrinogen-like, C-terminal
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion NAS
 biological_processGO:0007158 neuron cell-cell adhesion IEA
 biological_processGO:0007411 axon guidance NAS
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0022029 telencephalon cell migration IEA
 biological_processGO:0022408 negative regulation of cell-cell adhesion IEA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030517 negative regulation of axon extension IEA
 biological_processGO:0035641 locomotory exploration behavior IEA
 biological_processGO:0048692 negative regulation of axon extension involved in regeneration IEA
 biological_processGO:0050767 regulation of neurogenesis IEA
 biological_processGO:0050804 modulation of chemical synaptic transmission IEA
 biological_processGO:0050805 negative regulation of synaptic transmission IEA
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0050885 neuromuscular process controlling balance IEA
 biological_processGO:0051968 positive regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:0051971 positive regulation of transmission of nerve impulse IEA
 biological_processGO:0060291 long-term synaptic potentiation IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0072534 perineuronal net IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000116147 TNR / Q92752 / tenascin R  / complex
 ENSG00000115414 FN1 / P02751 / fibronectin 1  / complex / reaction






 

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