ENSG00000120158


Homo sapiens

Features
Gene ID: ENSG00000120158
  
Biological name :RCL1
  
Synonyms : Q9Y2P8 / RCL1 / RNA terminal phosphate cyclase like 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: p24.1
Gene start: 4792869
Gene end: 4885917
  
Corresponding Affymetrix probe sets: 218544_s_at (Human Genome U133 Plus 2.0 Array)   222666_s_at (Human Genome U133 Plus 2.0 Array)   233981_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000412000
Ensembl peptide - ENSP00000371147
Ensembl peptide - ENSP00000371149
Ensembl peptide - ENSP00000371151
Ensembl peptide - ENSP00000413381
Ensembl peptide - ENSP00000371169
Ensembl peptide - ENSP00000388096
NCBI entrez gene - 10171     See in Manteia.
OMIM - 611405
RefSeq - XM_017014176
RefSeq - NM_001286699
RefSeq - NM_001286700
RefSeq - NM_001286701
RefSeq - NM_005772
RefSeq - XM_006716715
RefSeq - XM_011517673
RefSeq Peptide - NP_005763
RefSeq Peptide - NP_001273628
RefSeq Peptide - NP_001273629
RefSeq Peptide - NP_001273630
swissprot - Q9Y2P8
swissprot - Q5VYW8
swissprot - Q5VZU2
swissprot - Q5VZU3
Ensembl - ENSG00000120158
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rcl1ENSDARG00000038312Danio rerio
 RCL1ENSGALG00000015024Gallus gallus
 Rcl1ENSMUSG00000024785Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RTCA / O00442 / RNA 3-terminal phosphate cyclaseENSG0000013799623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000228  RNA 3"-terminal phosphate cyclase
 IPR013791  RNA 3"-terminal phosphate cyclase, insert domain
 IPR013792  RNA 3"-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta
 IPR016443  RNA 3"-terminal phosphate cyclase type 2
 IPR020719  RNA 3"-terminal phosphate cyclase-like, conserved site
 IPR023797  RNA 3"-terminal phosphate cyclase domain
 IPR037136  RNA 3"-terminal phosphate cyclase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
 biological_processGO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0000480 endonucleolytic cleavage in 5"-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0042254 ribosome biogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004521 endoribonuclease activity IBA


Pathways (from Reactome)
Pathway description
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000165733 BMS1 / Q14692 / BMS1, ribosome biogenesis factor  / complex






 

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