ENSG00000121578


Homo sapiens

Features
Gene ID: ENSG00000121578
  
Biological name :B4GALT4
  
Synonyms : B4GALT4 / beta-1,4-galactosyltransferase 4 / O60513
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q13.32
Gene start: 119211732
Gene end: 119241103
  
Corresponding Affymetrix probe sets: 210540_s_at (Human Genome U133 Plus 2.0 Array)   212876_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417188
Ensembl peptide - ENSP00000417226
Ensembl peptide - ENSP00000420665
Ensembl peptide - ENSP00000420535
Ensembl peptide - ENSP00000420161
Ensembl peptide - ENSP00000419919
Ensembl peptide - ENSP00000419916
Ensembl peptide - ENSP00000419275
Ensembl peptide - ENSP00000418436
Ensembl peptide - ENSP00000418278
Ensembl peptide - ENSP00000417958
Ensembl peptide - ENSP00000417527
Ensembl peptide - ENSP00000352144
Ensembl peptide - ENSP00000377360
NCBI entrez gene - 8702     See in Manteia.
OMIM - 604015
RefSeq - XM_017007401
RefSeq - NM_003778
RefSeq - NM_212543
RefSeq - XM_005247855
RefSeq - XM_006713798
RefSeq - XM_006713799
RefSeq - XM_006713800
RefSeq - XM_006713801
RefSeq - XM_011513260
RefSeq Peptide - NP_003769
RefSeq Peptide - NP_997708
swissprot - E7ETS9
swissprot - C9JY38
swissprot - C9JY35
swissprot - C9JE00
swissprot - C9JA31
swissprot - C9J644
swissprot - C9J5S0
swissprot - C9J4S5
swissprot - B2RAZ5
swissprot - C9J3R8
swissprot - O60513
Ensembl - ENSG00000121578
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 b4galt4ENSDARG00000104042Danio rerio
 B4GALT4ENSGALG00000015069Gallus gallus
 Q9JJ04ENSMUSG00000022793Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60512 / B4GALT3 / beta-1,4-galactosyltransferase 3ENSG0000015885047
P15291 / B4GALT1 / beta-1,4-galactosyltransferase 1ENSG0000008606242
O60909 / B4GALT2 / beta-1,4-galactosyltransferase 2ENSG0000011741142
Q9UBX8 / B4GALT6 / beta-1,4-galactosyltransferase 6ENSG0000011827634
O43286 / B4GALT5 / beta-1,4-galactosyltransferase 5ENSG0000015847033
Q9UBV7 / B4GALT7 / beta-1,4-galactosyltransferase 7ENSG0000002784724


Protein motifs (from Interpro)
Interpro ID Name
 IPR003859  Beta-1,4-galactosyltransferase
 IPR027791  Galactosyltransferase, C-terminal
 IPR027995  Galactosyltransferase, N-terminal
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006643 membrane lipid metabolic process TAS
 biological_processGO:0018146 keratan sulfate biosynthetic process TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 molecular_functionGO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity TAS
 molecular_functionGO:0003945 N-acetyllactosamine synthase activity IEA
 molecular_functionGO:0008378 galactosyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
N-Glycan antennae elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000121578 O60513 / B4GALT4 / beta-1,4-galactosyltransferase 4  / complex






 

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