ENSG00000122482


Homo sapiens

Features
Gene ID: ENSG00000122482
  
Biological name :ZNF644
  
Synonyms : Q9H582 / zinc finger protein 644 / ZNF644
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p22.2
Gene start: 90915298
Gene end: 91022272
  
Corresponding Affymetrix probe sets: 1553725_s_at (Human Genome U133 Plus 2.0 Array)   222580_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000337008
Ensembl peptide - ENSP00000354659
Ensembl peptide - ENSP00000359469
Ensembl peptide - ENSP00000482748
Ensembl peptide - ENSP00000340828
NCBI entrez gene - 84146     See in Manteia.
OMIM - 614159
RefSeq - XM_017002494
RefSeq - NM_016620
RefSeq - NM_032186
RefSeq - NM_201269
RefSeq - XM_017002489
RefSeq - XM_017002490
RefSeq - XM_017002491
RefSeq - XM_017002492
RefSeq - XM_017002493
RefSeq - XM_005271257
RefSeq - XM_005271260
RefSeq - XM_011542258
RefSeq - XM_011542259
RefSeq - XM_011542260
RefSeq - XM_011542261
RefSeq - XM_017002487
RefSeq - XM_017002488
RefSeq Peptide - NP_057704
RefSeq Peptide - NP_115562
RefSeq Peptide - NP_958357
swissprot - Q9H582
swissprot - A0A087WZL9
Ensembl - ENSG00000122482
  
Related genetic diseases (OMIM): 614167 - Myopia 21, autosomal dominant, 614167

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 znf644aENSDARG00000101361Danio rerio
 znf644bENSDARG00000102025Danio rerio
 ZNF644ENSGALG00000034253Gallus gallus
 Zfp644ENSMUSG00000049606Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WIZ / O95785 / widely interspaced zinc finger motifsENSG000000114519


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000006 Autosomal dominant inheritance "A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in heterozygotes. In the context of medical genetics, an autosomal dominant disorder is caused when a single copy of the mutant allele is present. Males and females are affected equally, and can both transmit the disorder with a risk of 50% for each child of inheriting the mutant allele." [HPO:curators]
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 HP:0011003 Severe Myopia 
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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