ENSG00000122986


Homo sapiens

Features
Gene ID: ENSG00000122986
  
Biological name :HVCN1
  
Synonyms : HVCN1 / hydrogen voltage gated channel 1 / Q96D96
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.11
Gene start: 110627841
Gene end: 110704950
  
Corresponding Affymetrix probe sets: 226879_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479812
Ensembl peptide - ENSP00000449601
Ensembl peptide - ENSP00000450106
Ensembl peptide - ENSP00000242607
Ensembl peptide - ENSP00000349181
Ensembl peptide - ENSP00000412052
Ensembl peptide - ENSP00000447227
Ensembl peptide - ENSP00000448379
NCBI entrez gene - 84329     See in Manteia.
OMIM - 611227
RefSeq - XM_017020027
RefSeq - XM_011538841
RefSeq - XM_011538842
RefSeq - XM_011538844
RefSeq - XM_011538845
RefSeq - XM_011538846
RefSeq - XM_011538847
RefSeq - XM_017020026
RefSeq - NM_001040107
RefSeq - NM_001256413
RefSeq - NM_032369
RefSeq - XM_005253948
RefSeq - XM_011538838
RefSeq - XM_011538839
RefSeq - XM_011538840
RefSeq Peptide - NP_115745
RefSeq Peptide - NP_001035196
RefSeq Peptide - NP_001243342
swissprot - F8VPF7
swissprot - Q96D96
swissprot - F8W0B3
swissprot - F8VS40
Ensembl - ENSG00000122986
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hvcn1ENSDARG00000040338Danio rerio
 HVCN1ENSGALG00000004562Gallus gallus
 Hvcn1ENSMUSG00000064267Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q2M3C6 / TMEM266 / transmembrane protein 266ENSG0000016975820


Protein motifs (from Interpro)
Interpro ID Name
 IPR005821  Ion transport domain
 IPR031844  Voltage-gated hydrogen channel 1, C-terminal membrane-localisation domain
 IPR031846  Voltage-gated hydrogen channel 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0009268 response to pH ISS
 biological_processGO:0010043 response to zinc ion ISS
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0035036 sperm-egg recognition TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071294 cellular response to zinc ion IDA
 biological_processGO:0071467 cellular response to pH IDA
 biological_processGO:1902600 proton transmembrane transport ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0035579 specific granule membrane TAS
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0022843 voltage-gated cation channel activity TAS
 molecular_functionGO:0030171 voltage-gated proton channel activity ISS
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Sperm Motility And Taxes
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000122986 HVCN1 / Q96D96 / hydrogen voltage gated channel 1  / complex






 

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