ENSG00000123307


Homo sapiens

Features
Gene ID: ENSG00000123307
  
Biological name :NEUROD4
  
Synonyms : NEUROD4 / neuronal differentiation 4 / Q9HD90
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.2
Gene start: 55019945
Gene end: 55030014
  
Corresponding Affymetrix probe sets: 221318_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000242994
NCBI entrez gene - 58158     See in Manteia.
OMIM - 611635
RefSeq - NM_021191
RefSeq Peptide - NP_067014
swissprot - Q9HD90
Ensembl - ENSG00000123307
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neurod4ENSDARG00000003469Danio rerio
 NEUROD4ENSGALG00000034306Gallus gallus
 O09105ENSMUSG00000048015Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q13562 / NEUROD1 / neuronal differentiation 1ENSG0000016299254
Q15784 / NEUROD2 / neuronal differentiation 2ENSG0000017153245
Q96NK8 / NEUROD6 / neuronal differentiation 6ENSG0000016460043
Q92886 / NEUROG1 / neurogenin 1ENSG0000018196520
Q9H2A3 / NEUROG2 / neurogenin 2ENSG0000017840319
ATOH1 / Q92858 / atonal bHLH transcription factor 1ENSG0000017223818
Q9Y4Z2 / NEUROG3 / neurogenin 3ENSG0000012285916
ATOH8 / Q96SQ7 / atonal bHLH transcription factor 8ENSG0000016887414
Q7RTS1 / BHLHA15 / basic helix-loop-helix family member a15ENSG0000018053514
ATOH7 / Q8N100 / atonal bHLH transcription factor 7ENSG0000017977413


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR016637  Neurogenic differentiation factor NeuroD
 IPR022575  Neurogenic differentiation factor, domain of unknown function
 IPR032651  Neurogenic differentiation factor 4
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007405 neuroblast proliferation IEA
 biological_processGO:0010001 glial cell differentiation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035881 amacrine cell differentiation IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0045597 positive regulation of cell differentiation IEA
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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