ENSG00000126264


Homo sapiens
cellmembranebindingHCSTproteinregulationphosphatidylinositol-kinasesignalinghematopoieticsignaltransducerphosphorylationimmuneresponseplasmasurfaceintegralcomponentreceptorimmunoregulatoryinteractionslymphoidnon-lymphoid

Features
Gene ID: ENSG00000126264
  
Biological name :HCST
  
Synonyms : HCST / hematopoietic cell signal transducer / Q9UBK5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35902480
Gene end: 35904377
  
Corresponding Affymetrix probe sets: 223640_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000246551
Ensembl peptide - ENSP00000400516
NCBI entrez gene - 10870     See in Manteia.
OMIM - 604089
RefSeq - XM_017026193
RefSeq - NM_001007469
RefSeq - NM_014266
RefSeq Peptide - NP_055081
RefSeq Peptide - NP_001007470
swissprot - Q9UBK5
Ensembl - ENSG00000126264
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HcstENSMUSG00000064109Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009861  Hematopoietic cell signal transducer


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusimmune responsenitrogen compound menitrogen compound metabolic processcellular metabolic pcellular metabolic processprimary metabolic prprimary metabolic processorganic substance meorganic substance metabolic processcell communicationcell communicationcellular response tocellular response to stimulusimmune responseimmune response
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IGI
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding IDA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000213809 KLRK1 / P26718 / killer cell lectin like receptor K1  / complex
 ENSG00000126264 HCST / Q9UBK5 / hematopoietic cell signal transducer  / complex






 

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