ENSG00000129450


Homo sapiens
membraneSIGLEC9domaincellimmunoglobulinneutrophildegranulationplasmaintegralcomponentsubtypev-setfoldsuperfamilyadhesionsurfacereceptorsignalingpathwayregulationimmuneresponsesecretorygranulecarbohydratebindingimmunoregulatoryinteractionslymphoidnon-lymphoid

Features
Gene ID: ENSG00000129450
  
Biological name :SIGLEC9
  
Synonyms : Q9Y336 / sialic acid binding Ig like lectin 9 / SIGLEC9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.41
Gene start: 51124908
Gene end: 51136651
  
Corresponding Affymetrix probe sets: 210569_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000250360
Ensembl peptide - ENSP00000413861
Ensembl peptide - ENSP00000472483
NCBI entrez gene - 27180     See in Manteia.
OMIM - 605640
RefSeq - XM_017026596
RefSeq - NM_001198558
RefSeq - NM_014441
RefSeq - XM_006723146
RefSeq - XM_011526730
RefSeq - XM_011526732
RefSeq - XM_017026595
RefSeq Peptide - NP_001185487
RefSeq Peptide - NP_055256
swissprot - Q9Y336
swissprot - M0R2D4
Ensembl - ENSG00000129450
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-24p1.7ENSDARG00000089404Danio rerio
 Q91Y57ENSMUSG00000030474Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y286 / SIGLEC7 / sialic acid binding Ig like lectin 7ENSG0000016899569
Q96PQ1 / SIGLEC12 / sialic acid binding Ig like lectin 12 (gene/pseudogene)ENSG0000025452163
Q9NYZ4 / SIGLEC8 / sialic acid binding Ig like lectin 8ENSG0000010536662
O43699 / SIGLEC6 / sialic acid binding Ig like lectin 6ENSG0000010549244
O15389 / SIGLEC5 / sialic acid binding Ig like lectin 5ENSG0000010550142
AC018755.2ENSG0000026850042
Q08ET2 / SIGLEC14 / sialic acid binding Ig like lectin 14ENSG0000025441540
CD33 / P20138 / CD33 moleculeENSG0000010538339
Q96RL6 / SIGLEC11 / sialic acid binding Ig like lectin 11ENSG0000016164039
Q96LC7 / SIGLEC10 / sialic acid binding Ig like lectin 10ENSG0000014251238
MAG / P20916 / myelin associated glycoproteinENSG0000010569523
AC011452.1ENSG000002691790


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
cell adhesioncell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processcell adhesioncell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processcell adhesioncell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processcell adhesioncell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processcell adhesioncell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processcell adhesioncell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processcell adhesioncell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processcell adhesioncell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processcell adhesioncell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processcell adhesioncell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processcell adhesioncell adhesioncell communicationcell communicationcellular response tocellular response to stimulusimmune responseimmune responseestablishment of locestablishment of localizationcell activationcell activationimmune effector procimmune effector process
carbohydrate bindingcarbohydrate bindingcarbohydrate bindingcarbohydrate bindingcarbohydrate bindingcarbohydrate bindingcarbohydrate bindingcarbohydrate bindingcarbohydrate bindingcarbohydrate bindingcarbohydrate bindingcarbohydrate binding
cellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellcellmembranemembraneorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007166 cell surface receptor signaling pathway NAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030667 secretory granule membrane TAS
 molecular_functionGO:0030246 carbohydrate binding NAS


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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