ENSG00000130812
Homo sapiens fibrinogen c-terminal ANGPTL6 alpha beta gamma chain globular subdomain extracellular abnormality aortic domain conserved site fibrinogen-like angiogenesis multicellular organism development cell differentiation region secretory granule exosome hypertension visual field defects seizures
Features See expression report in BioGPS See gene description in Wikigenes See gene description in GeneCards See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl )Protein motifs (from Interpro ) IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain IPR014715 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2 IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 IPR020837 Fibrinogen, conserved site IPR036056 Fibrinogen-like, C-terminal
Gene Ontology (GO ) anatomical structure development cellular developmental process anatomical structure development cellular developmental process anatomical structure development cellular developmental process anatomical structure development cellular developmental process anatomical structure development cellular developmental process anatomical structure development cellular developmental process anatomical structure development cellular developmental process anatomical structure development cellular developmental process anatomical structure development cellular developmental process anatomical structure development cellular developmental process anatomical structure developmentanatomical structure development cellular developmental processcellular developmental process extracellular region cell organelle extracellular region cell organelle extracellular region cell organelle extracellular region cell organelle extracellular region cell organelle extracellular region cell organelle extracellular region cell organelle extracellular region cell organelle extracellular region cell organelle extracellular region cell organelle extracellular regionextracellular region cellcell organelleorganelle
Pathways (from Reactome )No match
Phenotype (from MGI , Zfin or HPO ) Abnormality of the cardiovascular system Abnormality of the eyes Neurological abnormality Hematological abnormality Abnormality of the cardiovascular system Abnormality of the eyes Neurological abnormality Hematological abnormality Abnormality of the cardiovascular system Abnormality of the eyes Neurological abnormality Hematological abnormality Abnormality of the cardiovascular system Abnormality of the eyes Neurological abnormality Hematological abnormality Abnormality of the cardiovascular system Abnormality of the eyes Neurological abnormality Hematological abnormality Abnormality of the cardiovascular system Abnormality of the eyes Neurological abnormality Hematological abnormality Abnormality of the cardiovascular system Abnormality of the eyes Neurological abnormality Hematological abnormality Abnormality of the cardiovascular system Abnormality of the eyes Neurological abnormality Hematological abnormality Abnormality of the cardiovascular system Abnormality of the eyes Neurological abnormality Hematological abnormality Abnormality of the cardiovascular system Abnormality of the eyes Neurological abnormality Hematological abnormality Abnormality of the cardiovascular sAbnormality of the cardiovascular system Abnormality of the eyesAbnormality of the eyes Neurological abnormalityNeurological abnormality Hematological abnormalityHematological abnormality HP:0000822 Hypertension "High blood pressure." [HPO:curators]
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HP:0001123 Visual field defects
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HP:0001250 Seizures "Seizures are an intermittent `abnormality of the central nervous system` (FMA:HP:0002011) due to a sudden, excessive, disorderly discharge of cerebral neurons and characterized clinically by some combination of disturbance of sensation, loss of consciousness, impairment of psychic function, or convulsive movements." [HPO:probinson]
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HP:0001269 Hemiparesis "Relatively mild weakness in the arm, leg, and in some cases the face on one side of the body." [HPO:curators]
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HP:0002138 Subarachnoid hemorrhage
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HP:0002326 Transient ischemic attack
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HP:0002363 Abnormality of the brainstem
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HP:0002616 Aortic root dilatation
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HP:0002621 Atherosclerosis "A condition characterized by patchy atheromas or atherosclerotic plaques which develop in the walls of medium-sized and large arteries and can lead to arterial stenosis with reduced or blocked blood flow." [HPO:curators]
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HP:0002647 Aortic dissection "Aortic dissection refers to a tear in the intimal layer of the aorta causing a separation between the intima and the medial layers of the aorta." [HPO:curators]
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HP:0007029 Cerebral berry aneurysms
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HP:0012246 Oculomotor nerve palsy "Reduced ability to control the movement of the eye associated with damage to the third cranial nerve (the oculomotor nerve)." [HPO:probinson]
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HP:0012518 Abnormality of circle of Willis "An anomaly of the `circle of Willis` (FMA:50454), also known as the cerebral arterial circle." [HPO:probinson]
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HP:0040197 Encephalomalacia "Encephalomalacia is the softening or loss of brain tissue after cerebral infarction, cerebral ischemia, infection, craniocerebral trauma, or other injury." [PhenoTips:CHum]
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Interacting proteins (from Reactome )No match
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