Manteia

ENSG00000131374

Homo sapiens

Features

Gene ID:	ENSG00000131374

Biological name :	TBC1D5

Synonyms :	Q92609 / TBC1D5 / TBC1 domain family member 5

Possible biological names infered from orthology :

Species:	Homo sapiens

Chr. number:	3
Strand:	-1
Band:	p24.3
Gene start:	17157162
Gene end:	18444817

Corresponding Affymetrix probe sets:	201813_s_at (Human Genome U133 Plus 2.0 Array) 201814_at (Human Genome U133 Plus 2.0 Array) 201815_s_at (Human Genome U133 Plus 2.0 Array)

Cross references:	Ensembl peptide - ENSP00000398127 Ensembl peptide - ENSP00000396850 Ensembl peptide - ENSP00000399967 Ensembl peptide - ENSP00000424998 Ensembl peptide - ENSP00000415379 Ensembl peptide - ENSP00000414250 Ensembl peptide - ENSP00000414159 Ensembl peptide - ENSP00000411925 Ensembl peptide - ENSP00000411780 Ensembl peptide - ENSP00000410596 Ensembl peptide - ENSP00000408603 Ensembl peptide - ENSP00000405886 Ensembl peptide - ENSP00000402935 Ensembl peptide - ENSP00000253692 Ensembl peptide - ENSP00000387395 Ensembl peptide - ENSP00000393882 Ensembl peptide - ENSP00000396239 NCBI entrez gene - 9779 See in Manteia. OMIM - 615740 RefSeq - XM_017007568 RefSeq - XM_005265615 RefSeq - XM_005265616 RefSeq - XM_006713430 RefSeq - XM_011534281 RefSeq - XM_011534283 RefSeq - XM_011534284 RefSeq - XM_011534286 RefSeq - XM_011534287 RefSeq - XM_017007552 RefSeq - XM_017007553 RefSeq - XM_017007554 RefSeq - XM_017007555 RefSeq - XM_017007556 RefSeq - XM_017007557 RefSeq - XM_017007558 RefSeq - XM_017007559 RefSeq - XM_017007560 RefSeq - XM_017007561 RefSeq - XM_017007562 RefSeq - XM_017007563 RefSeq - XM_017007564 RefSeq - XM_017007565 RefSeq - XM_017007566 RefSeq - XM_017007567 RefSeq - NM_001134381 RefSeq - NM_014744 RefSeq - XM_005265611 RefSeq - XM_005265612 RefSeq - XM_005265614 RefSeq Peptide - NP_001127853 RefSeq Peptide - NP_001336002 RefSeq Peptide - NP_001336003 RefSeq Peptide - NP_001336004 RefSeq Peptide - NP_001336005 RefSeq Peptide - NP_001336006 RefSeq Peptide - NP_001336007 RefSeq Peptide - NP_001336008 RefSeq Peptide - NP_001336009 RefSeq Peptide - NP_055559 swissprot - F2Z3C3 swissprot - F2Z3I5 swissprot - C9K0P2 swissprot - B9A6K1 swissprot - Q92609 swissprot - C9JWX0 swissprot - C9JW04 swissprot - C9JNM0 swissprot - C9JMP7 swissprot - C9JIU4 swissprot - C9JED7 swissprot - C9JDR8 swissprot - C9J3F6 swissprot - C9J397 Ensembl - ENSG00000131374

See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
tbc1d5	ENSDARG00000036212	Danio rerio
TBC1D5	ENSGALG00000011251	Gallus gallus
Q80XQ2	ENSMUSG00000023923	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q9NVG8 / TBC1D13 / TBC1 domain family member 13	ENSG00000107021	12

Protein motifs (from Interpro)

Interpro ID	Name
IPR000195	Rab-GTPase-TBC domain
IPR035969	Rab-GTPase-TBC domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0002092	positive regulation of receptor internalization	IMP
biological_process	GO:0006886	intracellular protein transport	IBA
biological_process	GO:0006914	autophagy	IDA
biological_process	GO:0015031	protein transport	IEA
biological_process	GO:0016236	macroautophagy	IMP
biological_process	GO:0031338	regulation of vesicle fusion	IBA
biological_process	GO:0042147	retrograde transport, endosome to Golgi	IMP
biological_process	GO:0042594	response to starvation	IDA
biological_process	GO:0090630	activation of GTPase activity	IBA
cellular_component	GO:0005768	endosome	IEA
cellular_component	GO:0005776	autophagosome	IEA
cellular_component	GO:0005794	Golgi apparatus	IDA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0010008	endosome membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0030122	AP-2 adaptor complex	IDA
cellular_component	GO:0030904	retromer complex	IDA
cellular_component	GO:0031410	cytoplasmic vesicle	IEA
cellular_component	GO:0043231	intracellular membrane-bounded organelle	IDA
cellular_component	GO:1990316	Atg1/ULK1 kinase complex	IDA
molecular_function	GO:0005096	GTPase activator activity	IBA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0017137	Rab GTPase binding	IBA
molecular_function	GO:0035612	AP-2 adaptor complex binding	IDA
molecular_function	GO:1905394	retromer complex binding	IMP

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr