ENSG00000132394


Homo sapiens

Features
Gene ID: ENSG00000132394
  
Biological name :EEFSEC
  
Synonyms : EEFSEC / eukaryotic elongation factor, selenocysteine-tRNA specific / P57772
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q21.3
Gene start: 128153454
Gene end: 128408646
  
Corresponding Affymetrix probe sets: 227540_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417660
Ensembl peptide - ENSP00000254730
NCBI entrez gene - 60678     See in Manteia.
OMIM - 607695
RefSeq - XM_017006980
RefSeq - NM_021937
RefSeq - XM_017006977
RefSeq - XM_017006978
RefSeq - XM_017006979
RefSeq - XM_005247696
RefSeq - XM_017006975
RefSeq - XM_017006976
RefSeq Peptide - NP_068756
swissprot - P57772
swissprot - C9J8T0
Ensembl - ENSG00000132394
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eefsecENSDARG00000004696Danio rerio
 EEFSECENSGALG00000038684Gallus gallus
 EefsecENSMUSG00000033216Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TUFM / P49411 / Tu translation elongation factor, mitochondrialENSG0000017895217


Protein motifs (from Interpro)
Interpro ID Name
 IPR000795  Transcription factor, GTP-binding domain
 IPR009000  Translation protein, beta-barrel domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001514 selenocysteine incorporation IEA
 biological_processGO:0006412 translation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003746 translation elongation factor activity IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0035368 selenocysteine insertion sequence binding IEA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IEA


Pathways (from Reactome)
Pathway description
Selenocysteine synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000187742 Q96T21 / SECISBP2 / SECIS binding protein 2  / complex / reaction






 

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