ENSG00000132793


Homo sapiens
processLPIN3lipinbiosyntheticactivitylnssuperfamilymetabolicfattyacidtriglyceridetranscriptionsynthesisn-terminalnedsmppitpmiddledomainhad-likelipidphosphatidylethanolaminephosphatidylcholinecatabolicdephosphorylationregulationrnapolymeraseiinucleusendoplasmic

Features
Gene ID: ENSG00000132793
  
Biological name :LPIN3
  
Synonyms : lipin 3 / LPIN3 / Q9BQK8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q12
Gene start: 41340920
Gene end: 41360582
  
Corresponding Affymetrix probe sets: 232966_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362354
Ensembl peptide - ENSP00000398092
Ensembl peptide - ENSP00000487971
NCBI entrez gene - 64900     See in Manteia.
OMIM - 605520
RefSeq - XM_017028020
RefSeq - NM_001301860
RefSeq - XM_011529003
RefSeq - XM_011529004
RefSeq - XM_011529005
RefSeq - XM_011528996
RefSeq - XM_011528997
RefSeq - XM_011528998
RefSeq - XM_011528999
RefSeq - XM_011529000
RefSeq - XM_011529001
RefSeq - XM_011529002
RefSeq Peptide - NP_001288789
swissprot - Q9BQK8
swissprot - H0Y5E1
Ensembl - ENSG00000132793
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:123305ENSDARG00000015563Danio rerio
 Lpin3ENSMUSG00000027412Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LPIN2 / Q92539 / lipin 2ENSG0000010157746
LPIN1 / Q14693 / lipin 1ENSG0000013432445


Protein motifs (from Interpro)
Interpro ID Name
 IPR007651  Lipin, N-terminal
 IPR013209  Lipin/Ned1/Smp2 (LNS2)
 IPR023214  HAD superfamily
 IPR031315  LNS2/PITP
 IPR031703  Lipin, middle domain
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
primary metabolic processorganic substance metabolic processcellular metabolic processsmall molecule metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processsmall molecule metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processsmall molecule metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processsmall molecule metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processsmall molecule metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processsmall molecule metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processsmall molecule metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processsmall molecule metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processsmall molecule metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processsmall molecule metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processprimary metabolic prprimary metabolic processorganic substance meorganic substance metabolic processcellular metabolic pcellular metabolic processsmall molecule metabsmall molecule metabolic processbiosynthetic processbiosynthetic processnitrogen compound menitrogen compound metabolic processcatabolic processcatabolic process
transcription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activitytranscription coregulator activityhydrolase activityhydrolase activity
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006646 phosphatidylethanolamine biosynthetic process TAS
 biological_processGO:0006656 phosphatidylcholine biosynthetic process TAS
 biological_processGO:0009062 fatty acid catabolic process IBA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0019432 triglyceride biosynthetic process IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 molecular_functionGO:0003713 transcription coactivator activity IBA
 molecular_functionGO:0008195 phosphatidate phosphatase activity EXP
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PC
Synthesis of PE
Depolymerisation of the Nuclear Lamina
Triglyceride biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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