ENSG00000135823


Homo sapiens

Features
Gene ID: ENSG00000135823
  
Biological name :STX6
  
Synonyms : O43752 / STX6 / syntaxin 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q25.3
Gene start: 180972712
Gene end: 181023121
  
Corresponding Affymetrix probe sets: 1552618_at (Human Genome U133 Plus 2.0 Array)   212799_at (Human Genome U133 Plus 2.0 Array)   212800_at (Human Genome U133 Plus 2.0 Array)   214441_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258301
Ensembl peptide - ENSP00000440188
NCBI entrez gene - 10228     See in Manteia.
OMIM - 603944
RefSeq - XM_017000007
RefSeq - NM_001286210
RefSeq - NM_005819
RefSeq - XM_011509058
RefSeq - XM_011509059
RefSeq - XM_017000006
RefSeq Peptide - NP_005810
RefSeq Peptide - NP_001273139
swissprot - O43752
Ensembl - ENSG00000135823
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stx6ENSDARG00000042742Danio rerio
 STX6ENSGALG00000003880Gallus gallus
 Stx6ENSMUSG00000026470Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STX10 / O60499 / syntaxin 10ENSG0000010491560


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR006012  Syntaxin/epimorphin, conserved site
 IPR010989  SNARE
 IPR015260  Syntaxin 6, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0006906 vesicle fusion IPI
 biological_processGO:0007032 endosome organization IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0032456 endocytic recycling IMP
 biological_processGO:0032880 regulation of protein localization IMP
 biological_processGO:0042147 retrograde transport, endosome to Golgi IMP
 biological_processGO:0048193 Golgi vesicle transport IEA
 biological_processGO:0048278 vesicle docking IBA
 biological_processGO:0090161 Golgi ribbon formation IMP
 biological_processGO:1903827 regulation of cellular protein localization IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0030136 clathrin-coated vesicle TAS
 cellular_componentGO:0030285 integral component of synaptic vesicle membrane IEA
 cellular_componentGO:0031201 SNARE complex IDA
 cellular_componentGO:0032588 trans-Golgi network membrane ISS
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005484 SNAP receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019905 syntaxin binding IPI


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105402 NAPA / P54920 / NSF attachment protein alpha  / complex / reaction
 ENSG00000117533 VAMP4 / O75379 / vesicle associated membrane protein 4  / complex
 ENSG00000124222 STX16 / O14662 / syntaxin 16  / complex
 ENSG00000151532 VTI1A / Q96AJ9 / vesicle transport through interaction with t-SNAREs 1A  / complex
 ENSG00000073969 NSF / P46459 / N-ethylmaleimide sensitive factor, vesicle fusing ATPase  / complex / reaction






 

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