ENSG00000136045


Homo sapiens

Features
Gene ID: ENSG00000136045
  
Biological name :PWP1
  
Synonyms : PWP1 / PWP1 homolog, endonuclein / Q13610
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q23.3
Gene start: 107685732
Gene end: 107713167
  
Corresponding Affymetrix probe sets: 201606_s_at (Human Genome U133 Plus 2.0 Array)   201607_at (Human Genome U133 Plus 2.0 Array)   201608_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000447770
Ensembl peptide - ENSP00000387365
Ensembl peptide - ENSP00000448227
Ensembl peptide - ENSP00000445249
NCBI entrez gene - 11137     See in Manteia.
RefSeq - NM_007062
RefSeq - NM_001317962
RefSeq - NM_001317963
RefSeq Peptide - NP_001304891
RefSeq Peptide - NP_008993
RefSeq Peptide - NP_001304892
swissprot - Q13610
swissprot - A0A024RBH5
swissprot - B4DJV5
swissprot - F8VZ56
Ensembl - ENSG00000136045
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pwp1ENSDARG00000015921Danio rerio
 PWP1ENSGALG00000012631Gallus gallus
 Pwp1ENSMUSG00000001785Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated TAS
 biological_processGO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein IEA
 biological_processGO:0034773 histone H4-K20 trimethylation IEA
 biological_processGO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I IDA
 biological_processGO:2000738 positive regulation of stem cell differentiation IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:1990889 H4K20me3 modified histone binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr