ENSG00000136828


Homo sapiens

Features
Gene ID: ENSG00000136828
  
Biological name :RALGPS1
  
Synonyms : Q5JS13 / Ral GEF with PH domain and SH3 binding motif 1 / RALGPS1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q33.3
Gene start: 126914774
Gene end: 127223166
  
Corresponding Affymetrix probe sets: 1554745_at (Human Genome U133 Plus 2.0 Array)   1555452_at (Human Genome U133 Plus 2.0 Array)   204199_at (Human Genome U133 Plus 2.0 Array)   210552_s_at (Human Genome U133 Plus 2.0 Array)   242689_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000415630
Ensembl peptide - ENSP00000259351
Ensembl peptide - ENSP00000317149
Ensembl peptide - ENSP00000362533
Ensembl peptide - ENSP00000362535
Ensembl peptide - ENSP00000377579
Ensembl peptide - ENSP00000377590
Ensembl peptide - ENSP00000404021
NCBI entrez gene - 9649     See in Manteia.
OMIM - 614444
RefSeq - NM_014636
RefSeq - XM_017015350
RefSeq - NM_001190728
RefSeq - NM_001190729
RefSeq - NM_001190730
RefSeq - NM_001322320
RefSeq - NM_001322321
RefSeq - NM_001322322
RefSeq - NM_001322323
RefSeq - NM_001322324
RefSeq - NM_001322325
RefSeq - XM_011519233
RefSeq - XM_011519234
RefSeq - XM_011519235
RefSeq - XM_011519236
RefSeq - XM_011519238
RefSeq - XM_017015342
RefSeq - XM_017015343
RefSeq - XM_017015344
RefSeq - XM_017015345
RefSeq - XM_017015346
RefSeq - XM_017015347
RefSeq - XM_017015348
RefSeq - XM_017015349
RefSeq - XM_006717328
RefSeq - XM_011519225
RefSeq - XM_011519226
RefSeq - XM_011519227
RefSeq - XM_011519228
RefSeq - XM_011519229
RefSeq - XM_011519230
RefSeq - XM_011519231
RefSeq - XM_011519232
RefSeq Peptide - NP_001177657
RefSeq Peptide - NP_001177658
RefSeq Peptide - NP_001177659
RefSeq Peptide - NP_001309249
RefSeq Peptide - NP_001309250
RefSeq Peptide - NP_001309251
RefSeq Peptide - NP_001309252
RefSeq Peptide - NP_001309253
RefSeq Peptide - NP_001309254
RefSeq Peptide - NP_055451
swissprot - Q5JS13
swissprot - Q5JT61
swissprot - H0Y6A2
Ensembl - ENSG00000136828
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B0UXH6ENSDARG00000068370Danio rerio
 RALGPS1ENSGALG00000000906Gallus gallus
 A2AR50ENSMUSG00000038831Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q86X27 / RALGPS2 / Ral GEF with PH domain and SH3 binding motif 2ENSG0000011619164
Q12967 / RALGDS / ral guanine nucleotide dissociation stimulatorENSG0000016027122
RGL3 / Q3MIN7 / ral guanine nucleotide dissociation stimulator like 3ENSG0000020551722
AL162417.1ENSG0000028524522
RGL1 / Q9NZL6 / ral guanine nucleotide dissociation stimulator like 1ENSG0000014334421
RGL2 / O15211 / ral guanine nucleotide dissociation stimulator like 2ENSG0000023744119
SOS2 / Q07890 / SOS Ras/Rho guanine nucleotide exchange factor 2ENSG0000010048517
SOS1 / Q07889 / SOS Ras/Rac guanine nucleotide exchange factor 1ENSG0000011590417
Q13972 / RASGRF1 / Ras protein specific guanine nucleotide releasing factor 1ENSG0000005833515
Q13905 / RAPGEF1 / Rap guanine nucleotide exchange factor 1ENSG0000010726315
O14827 / RASGRF2 / Ras protein specific guanine nucleotide releasing factor 2ENSG0000011331915
RGL4 / Q8IZJ4 / ral guanine nucleotide dissociation stimulator like 4ENSG0000015949614


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR011993  PH-like domain superfamily
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0032485 regulation of Ral protein signal transduction IDA
 biological_processGO:0035556 intracellular signal transduction NAS
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity NAS
 molecular_functionGO:0008321 Ral guanyl-nucleotide exchange factor activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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