ENSG00000143344


Homo sapiens

Features
Gene ID: ENSG00000143344
  
Biological name :RGL1
  
Synonyms : Q9NZL6 / ral guanine nucleotide dissociation stimulator like 1 / RGL1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q25.3
Gene start: 183636085
Gene end: 183928531
  
Corresponding Affymetrix probe sets: 209568_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000354097
Ensembl peptide - ENSP00000303192
NCBI entrez gene - 23179     See in Manteia.
OMIM - 605667
RefSeq - NM_001297672
RefSeq - NM_015149
RefSeq - XM_017000756
RefSeq - NM_001297669
RefSeq - NM_001297670
RefSeq - NM_001297671
RefSeq - XM_011509339
RefSeq - XM_011509341
RefSeq - XM_011509342
RefSeq Peptide - NP_055964
RefSeq Peptide - NP_001284598
RefSeq Peptide - NP_001284599
RefSeq Peptide - NP_001284600
RefSeq Peptide - NP_001284601
swissprot - Q9NZL6
Ensembl - ENSG00000143344
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgl1ENSDARG00000005989Danio rerio
 RGL1ENSGALG00000004728Gallus gallus
 Rgl1ENSMUSG00000026482Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q12967 / RALGDS / ral guanine nucleotide dissociation stimulatorENSG0000016027147
AL162417.1ENSG0000028524547
RGL3 / Q3MIN7 / ral guanine nucleotide dissociation stimulator like 3ENSG0000020551734
RGL2 / O15211 / ral guanine nucleotide dissociation stimulator like 2ENSG0000023744131
SOS2 / Q07890 / SOS Ras/Rho guanine nucleotide exchange factor 2ENSG0000010048518
SOS1 / Q07889 / SOS Ras/Rac guanine nucleotide exchange factor 1ENSG0000011590418
RGL4 / Q8IZJ4 / ral guanine nucleotide dissociation stimulator like 4ENSG0000015949618
O14827 / RASGRF2 / Ras protein specific guanine nucleotide releasing factor 2ENSG0000011331916
Q13972 / RASGRF1 / Ras protein specific guanine nucleotide releasing factor 1ENSG0000005833515
Q86X27 / RALGPS2 / Ral GEF with PH domain and SH3 binding motif 2ENSG0000011619115
Q13905 / RAPGEF1 / Rap guanine nucleotide exchange factor 1ENSG0000010726314
Q5JS13 / RALGPS1 / Ral GEF with PH domain and SH3 binding motif 1ENSG0000013682814


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000651  Ras-like guanine nucleotide exchange factor, N-terminal
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR019804  Ras guanine-nucleotide exchange factor, conserved site
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR029071  Ubiquitin-like domain superfamily
 IPR030748  Ral guanine nucleotide dissociation stimulator-like 1
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007264 small GTPase mediated signal transduction NAS
 biological_processGO:0019216 regulation of lipid metabolic process TAS
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008321 Ral guanyl-nucleotide exchange factor activity NAS


Pathways (from Reactome)
Pathway description
PPARA activates gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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