ENSG00000138771


Homo sapiens
cellSHROOM3domainapicaljunctionbindingpdzapxshrmshroomdevelopmentproteinactinfamilysuperfamilymorphogenesisneuraltubeclosureepithelialmulticellularorganismpatternspecificationprocessregulationshapecellularpigmentaccumulationlocalization

Features
Gene ID: ENSG00000138771
  
Biological name :SHROOM3
  
Synonyms : Q8TF72 / SHROOM3 / shroom family member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q21.1
Gene start: 76435100
Gene end: 76783253
  
Corresponding Affymetrix probe sets: 225548_at (Human Genome U133 Plus 2.0 Array)   228400_at (Human Genome U133 Plus 2.0 Array)   243653_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000296043
Ensembl peptide - ENSP00000494970
Ensembl peptide - ENSP00000496523
NCBI entrez gene - 57619     See in Manteia.
OMIM - 604570
RefSeq - XM_017008489
RefSeq - NM_020859
RefSeq - XM_011532161
RefSeq - XM_017008488
RefSeq - XM_005263163
RefSeq - XM_005263164
RefSeq - XM_005263165
RefSeq - XM_006714282
RefSeq - XM_011532157
RefSeq - XM_011532158
RefSeq - XM_011532159
RefSeq - XM_011532160
RefSeq Peptide - NP_065910
swissprot - Q8TF72
Ensembl - ENSG00000138771
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 shroom3ENSDARG00000102180Danio rerio
 ENSGALG00000042427Gallus gallus
 Shroom3ENSMUSG00000029381Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q13796 / SHROOM2 / shroom family member 2ENSG0000014695026
Q9ULL8 / SHROOM4 / shroom family member 4ENSG0000015835221
Q2M3G4 / SHROOM1 / shroom family member 1ENSG0000016440312


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR014799  Apx/Shrm Domain 2
 IPR014800  Apx/Shrm Domain 1
 IPR027685  Shroom family
 IPR030494  Shroom3
 IPR036034  PDZ superfamily


Gene Ontology (GO)
cellular component organizationanatomical structure developmentcellular developmental processregulation of biological qualityresponse to external stimuluscellular pigmentationcellular response to stimulusmacromolecule localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of biological qualityresponse to external stimuluscellular pigmentationcellular response to stimulusmacromolecule localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of biological qualityresponse to external stimuluscellular pigmentationcellular response to stimulusmacromolecule localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of biological qualityresponse to external stimuluscellular pigmentationcellular response to stimulusmacromolecule localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of biological qualityresponse to external stimuluscellular pigmentationcellular response to stimulusmacromolecule localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of biological qualityresponse to external stimuluscellular pigmentationcellular response to stimulusmacromolecule localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of biological qualityresponse to external stimuluscellular pigmentationcellular response to stimulusmacromolecule localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of biological qualityresponse to external stimuluscellular pigmentationcellular response to stimulusmacromolecule localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of biological qualityresponse to external stimuluscellular pigmentationcellular response to stimulusmacromolecule localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of biological qualityresponse to external stimuluscellular pigmentationcellular response to stimulusmacromolecule localizationcellular componencellular component organizationanatomical structanatomical structure developmentcellular developmcellular developmental processregulation of bioregulation of biological qualityresponse to exterresponse to external stimuluscellular pigmentacellular pigmentationcellular responsecellular response to stimulusmacromolecule locmacromolecule localization
protein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein bindingprotein-containing complex bindingprotein-containing complex binding
cellorganellesupramolecular complexcell junctionmembranecellorganellesupramolecular complexcell junctionmembranecellorganellesupramolecular complexcell junctionmembranecellorganellesupramolecular complexcell junctionmembranecellorganellesupramolecular complexcell junctionmembranecellorganellesupramolecular complexcell junctionmembranecellorganellesupramolecular complexcell junctionmembranecellorganellesupramolecular complexcell junctionmembranecellorganellesupramolecular complexcell junctionmembranecellorganellesupramolecular complexcell junctionmembranecellcellorganelleorganellesupramolecular complexsupramolecular complexcell junctioncell junctionmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0002064 epithelial cell development IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007389 pattern specification process ISS
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0043482 cellular pigment accumulation ISS
 biological_processGO:0045176 apical protein localization ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton ISS
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005912 adherens junction ISS
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043296 apical junction complex ISS
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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