ENSG00000141434


Homo sapiens

Features
Gene ID: ENSG00000141434
  
Biological name :MEP1B
  
Synonyms : MEP1B / meprin A subunit beta / Q16820
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q12.1
Gene start: 32185069
Gene end: 32220404
  
Corresponding Affymetrix probe sets: 207251_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000269202
Ensembl peptide - ENSP00000462038
Ensembl peptide - ENSP00000463280
NCBI entrez gene - 4225     See in Manteia.
OMIM - 600389
RefSeq - XM_011526014
RefSeq - NM_001308171
RefSeq - NM_005925
RefSeq - XM_011526013
RefSeq Peptide - NP_001295100
RefSeq Peptide - NP_005916
swissprot - J3QKX5
swissprot - Q16820
swissprot - J3KRK1
Ensembl - ENSG00000141434
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mep1bENSDARG00000037533Danio rerio
 si:ch73-40a17.3ENSDARG00000040683Danio rerio
 MEP1BENSGALG00000044606Gallus gallus
 Mep1bENSMUSG00000024313Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MEP1A / Q16819 / meprin A subunit alphaENSG0000011281842
ASTL / Q6HA08 / astacin like metalloendopeptidaseENSG0000018888616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR000998  MAM domain
 IPR001506  Peptidase M12A
 IPR002083  MATH/TRAF domain
 IPR006026  Peptidase, metallopeptidase
 IPR008294  Meprin alpha/beta subunit
 IPR008974  TRAF-like
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034038  Meprin peptidase domain
 IPR034302  Meprin beta subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:1901998 toxin transport IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017090 meprin A complex IDA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr