ENSG00000141580


Homo sapiens

Features
Gene ID: ENSG00000141580
  
Biological name :WDR45B
  
Synonyms : Q5MNZ6 / WDR45B / WD repeat domain 45B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.3
Gene start: 82614562
Gene end: 82648553
  
Corresponding Affymetrix probe sets: 209076_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376139
Ensembl peptide - ENSP00000460297
Ensembl peptide - ENSP00000461355
Ensembl peptide - ENSP00000461488
Ensembl peptide - ENSP00000458738
NCBI entrez gene - 56270     See in Manteia.
OMIM - 609226
RefSeq - XM_017024863
RefSeq - NM_019613
RefSeq - XM_005256377
RefSeq - XM_017024862
RefSeq Peptide - NP_062559
swissprot - A0A024R8U4
swissprot - I3L4S6
swissprot - I3L1D0
swissprot - I3L3A5
swissprot - I3L4L8
swissprot - Q5MNZ6
Ensembl - ENSG00000141580
  
Related genetic diseases (OMIM): 617977 - Neurodevelopmental disorder with spastic quadriplegia and brain abnormalities with or without seizures, 617977
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wdr45bENSDARG00000021557Danio rerio
 Q5ZL16ENSGALG00000001563Gallus gallus
 Q9CR39ENSMUSG00000025173Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WDR45 / Q9Y484 / WD repeat domain 45ENSG0000019699848


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006497 protein lipidation IBA
 biological_processGO:0034497 protein localization to phagophore assembly site IBA
 biological_processGO:0044804 autophagy of nucleus IBA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0019898 extrinsic component of membrane IBA
 cellular_componentGO:0034045 phagophore assembly site membrane IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IBA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IBA


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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