ENSG00000143851


Homo sapiens

Features
Gene ID: ENSG00000143851
  
Biological name :PTPN7
  
Synonyms : P35236 / protein tyrosine phosphatase, non-receptor type 7 / PTPN7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.1
Gene start: 202147013
Gene end: 202161588
  
Corresponding Affymetrix probe sets: 1554860_at (Human Genome U133 Plus 2.0 Array)   204852_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418416
Ensembl peptide - ENSP00000418837
Ensembl peptide - ENSP00000485691
Ensembl peptide - ENSP00000420506
Ensembl peptide - ENSP00000420434
Ensembl peptide - ENSP00000419993
Ensembl peptide - ENSP00000419733
Ensembl peptide - ENSP00000419523
Ensembl peptide - ENSP00000419196
Ensembl peptide - ENSP00000309116
Ensembl peptide - ENSP00000356248
Ensembl peptide - ENSP00000406042
Ensembl peptide - ENSP00000417350
Ensembl peptide - ENSP00000417410
Ensembl peptide - ENSP00000418129
NCBI entrez gene - 5778     See in Manteia.
OMIM - 176889
RefSeq - XM_017001937
RefSeq - NM_001199797
RefSeq - NM_002832
RefSeq - NM_080588
RefSeq - XM_011509819
RefSeq - XM_011509820
RefSeq - XM_011509821
RefSeq - XM_011509822
RefSeq - XM_011509823
RefSeq - XM_011509824
RefSeq - XM_017001935
RefSeq - XM_017001936
RefSeq Peptide - NP_002823
RefSeq Peptide - NP_542155
RefSeq Peptide - NP_001186726
swissprot - E7EUM0
swissprot - C9JBA9
swissprot - C9JAW7
swissprot - C9IYI6
swissprot - A0A024R9A7
swissprot - A0A024R963
swissprot - F8WEY3
swissprot - F8WF08
swissprot - F8WF66
swissprot - H7C4T8
swissprot - J3KR55
swissprot - H7C5I3
swissprot - P35236
swissprot - E9PE54
Ensembl - ENSG00000143851
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTPN7ENSGALG00000036093Gallus gallus
 Ptpn7ENSMUSG00000031506Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPRR / Q15256 / protein tyrosine phosphatase, receptor type RENSG0000015323344
PTPN5 / P54829 / protein tyrosine phosphatase, non-receptor type 5ENSG0000011078640
PTPN11 / Q06124 / protein tyrosine phosphatase, non-receptor type 11ENSG0000017929525
PTPN6 / P29350 / protein tyrosine phosphatase, non-receptor type 6ENSG0000011167924
PTPRN2 / Q92932 / protein tyrosine phosphatase, receptor type N2ENSG0000015509324
PTPRN / Q16849 / protein tyrosine phosphatase, receptor type NENSG0000005435623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR008356  Protein-tyrosine phosphatase, KIM-containing
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0071345 cellular response to cytokine stimulus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-37 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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