ENSG00000153233


Homo sapiens

Features
Gene ID: ENSG00000153233
  
Biological name :PTPRR
  
Synonyms : protein tyrosine phosphatase, receptor type R / PTPRR / Q15256
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q15
Gene start: 70638073
Gene end: 70920843
  
Corresponding Affymetrix probe sets: 206084_at (Human Genome U133 Plus 2.0 Array)   210675_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449616
Ensembl peptide - ENSP00000446943
Ensembl peptide - ENSP00000448049
Ensembl peptide - ENSP00000283228
Ensembl peptide - ENSP00000339605
Ensembl peptide - ENSP00000368054
Ensembl peptide - ENSP00000391750
NCBI entrez gene - 5801     See in Manteia.
OMIM - 602853
RefSeq - XM_011538615
RefSeq - NM_001207015
RefSeq - NM_001207016
RefSeq - NM_002849
RefSeq - NM_130846
RefSeq Peptide - NP_002840
RefSeq Peptide - NP_570897
RefSeq Peptide - NP_001193945
RefSeq Peptide - NP_001193944
swissprot - F8VVE9
swissprot - F8VU63
swissprot - Q15256
Ensembl - ENSG00000153233
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptprrENSDARG00000105744Danio rerio
 ENSGALG00000010148Gallus gallus
 ENSGALG00000040855Gallus gallus
 PtprrENSMUSG00000020151Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPN5 / P54829 / protein tyrosine phosphatase, non-receptor type 5ENSG0000011078637
PTPN7 / P35236 / protein tyrosine phosphatase, non-receptor type 7ENSG0000014385131
PTPRN / Q16849 / protein tyrosine phosphatase, receptor type NENSG0000005435622
PTPRN2 / Q92932 / protein tyrosine phosphatase, receptor type N2ENSG0000015509320
PTPN11 / Q06124 / protein tyrosine phosphatase, non-receptor type 11ENSG0000017929520
PTPN6 / P29350 / protein tyrosine phosphatase, non-receptor type 6ENSG0000011167918


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR008356  Protein-tyrosine phosphatase, KIM-containing
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR016334  Protein-tyrosine phosphatase, receptor type R/non-receptor type 5
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEP
 biological_processGO:0006470 protein dephosphorylation TAS
 biological_processGO:0010633 negative regulation of epithelial cell migration IMP
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0038128 ERBB2 signaling pathway IMP
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IMP
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005001 transmembrane receptor protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0019901 protein kinase binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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