ENSG00000145287


Homo sapiens

Features
Gene ID: ENSG00000145287
  
Biological name :PLAC8
  
Synonyms : PLAC8 / placenta specific 8 / Q9NZF1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q21.22
Gene start: 83090048
Gene end: 83137075
  
Corresponding Affymetrix probe sets: 219014_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000309509
Ensembl peptide - ENSP00000412230
Ensembl peptide - ENSP00000422526
Ensembl peptide - ENSP00000423459
Ensembl peptide - ENSP00000399700
NCBI entrez gene - 51316     See in Manteia.
OMIM - 607515
RefSeq - NM_001130715
RefSeq - NM_001130716
RefSeq - NM_016619
RefSeq Peptide - NP_001124187
RefSeq Peptide - NP_001124188
RefSeq Peptide - NP_057703
swissprot - X2BQ60
swissprot - D6RA24
swissprot - Q9NZF1
Ensembl - ENSG00000145287
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plac8.1ENSDARG00000043729Danio rerio
 plac8.2ENSDARG00000094438Danio rerio
 ENSGALG00000011190Gallus gallus
 PLAC8L1ENSGALG00000020193Gallus gallus
 Plac8ENSMUSG00000029322Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CNFN / Q9BYD5 / cornifelinENSG0000010542737
A1L4L8 / PLAC8L1 / PLAC8 like 1ENSG0000017326131


Protein motifs (from Interpro)
Interpro ID Name
 IPR006461  PLAC8 motif-containing protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0009409 response to cold IEA
 biological_processGO:0040015 negative regulation of multicellular organism growth IEA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050873 brown fat cell differentiation IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0035578 azurophil granule lumen TAS
 molecular_functionGO:0003682 chromatin binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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