ENSG00000145833


Homo sapiens

Features
Gene ID: ENSG00000145833
  
Biological name :DDX46
  
Synonyms : DDX46 / DEAD-box helicase 46 / Q7L014
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q31.1
Gene start: 134758771
Gene end: 134855133
  
Corresponding Affymetrix probe sets: 1553107_s_at (Human Genome U133 Plus 2.0 Array)   202462_s_at (Human Genome U133 Plus 2.0 Array)   228039_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427290
Ensembl peptide - ENSP00000425073
Ensembl peptide - ENSP00000487025
Ensembl peptide - ENSP00000426767
Ensembl peptide - ENSP00000346236
Ensembl peptide - ENSP00000416534
NCBI entrez gene - 9879     See in Manteia.
OMIM - 617848
RefSeq - XM_011543758
RefSeq - NM_001300860
RefSeq - NM_014829
RefSeq Peptide - NP_001287789
RefSeq Peptide - NP_055644
swissprot - D6RJA6
swissprot - H0YAD5
swissprot - H0Y9U3
swissprot - A0A0C4DG89
swissprot - Q7L014
Ensembl - ENSG00000145833
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx46ENSDARG00000099458Danio rerio
 DDX46ENSGALG00000006404Gallus gallus
 Ddx46ENSMUSG00000021500Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036612  K Homology domain, type 1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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