ENSG00000147862


Homo sapiens

Features
Gene ID: ENSG00000147862
  
Biological name :NFIB
  
Synonyms : NFIB / nuclear factor I B / O00712
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: p22.3
Gene start: 14081843
Gene end: 14398983
  
Corresponding Affymetrix probe sets: 209289_at (Human Genome U133 Plus 2.0 Array)   209290_s_at (Human Genome U133 Plus 2.0 Array)   211466_at (Human Genome U133 Plus 2.0 Array)   211467_s_at (Human Genome U133 Plus 2.0 Array)   213029_at (Human Genome U133 Plus 2.0 Array)   213032_at (Human Genome U133 Plus 2.0 Array)   213033_s_at (Human Genome U133 Plus 2.0 Array)   233304_at (Human Genome U133 Plus 2.0 Array)   233394_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000475362
Ensembl peptide - ENSP00000496424
Ensembl peptide - ENSP00000490950
Ensembl peptide - ENSP00000490945
Ensembl peptide - ENSP00000490864
Ensembl peptide - ENSP00000490762
Ensembl peptide - ENSP00000490588
Ensembl peptide - ENSP00000490020
Ensembl peptide - ENSP00000489634
Ensembl peptide - ENSP00000481181
Ensembl peptide - ENSP00000475813
Ensembl peptide - ENSP00000370308
Ensembl peptide - ENSP00000370311
Ensembl peptide - ENSP00000370321
Ensembl peptide - ENSP00000370340
Ensembl peptide - ENSP00000370346
Ensembl peptide - ENSP00000380705
Ensembl peptide - ENSP00000380709
Ensembl peptide - ENSP00000380711
Ensembl peptide - ENSP00000442888
NCBI entrez gene - 4781     See in Manteia.
OMIM - 600728
RefSeq - NM_005596
RefSeq - NM_001190738
RefSeq - XM_017014741
RefSeq - XM_017014742
RefSeq - NM_001190737
RefSeq - NM_001282787
RefSeq - XM_005251467
RefSeq - XM_005251468
RefSeq - XM_005251469
RefSeq - XM_005251470
RefSeq - XM_005251471
RefSeq - XM_006716773
RefSeq - XM_006716774
RefSeq - XM_006716775
RefSeq - XM_017014739
RefSeq - XM_017014740
RefSeq Peptide - NP_001177667
RefSeq Peptide - NP_001269716
RefSeq Peptide - NP_005587
RefSeq Peptide - NP_001177666
swissprot - Q5VW26
swissprot - A0A1B0GWI9
swissprot - A0A1B0GWB8
swissprot - A0A1B0GW37
swissprot - A0A1B0GVN4
swissprot - A0A1B0GU97
swissprot - A0A1B0GTC1
swissprot - A0A0A0MRX8
swissprot - A0A087WXP2
swissprot - O00712
swissprot - A0A1B0GWJ4
swissprot - Q5VW27
swissprot - Q5VW28
swissprot - Q5VW30
swissprot - Q5VW31
swissprot - Q5W0Y9
swissprot - U3KPY9
swissprot - U3KQE8
Ensembl - ENSG00000147862
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NFIBENSGALG00000005441Gallus gallus
 NfibENSMUSG00000008575Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NFIA / Q12857 / nuclear factor I AENSG0000016259962
NFIC / P08651 / nuclear factor I CENSG0000014190554
NFIX / Q14938 / nuclear factor I XENSG0000000844152


Protein motifs (from Interpro)
Interpro ID Name
 IPR000647  CTF transcription factor/nuclear factor 1
 IPR003619  MAD homology 1, Dwarfin-type
 IPR019548  CTF transcription factor/nuclear factor 1, N-terminal
 IPR019739  CTF transcription factor/nuclear factor 1, conserved site
 IPR020604  CTF transcription factor/nuclear factor 1, DNA-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002062 chondrocyte differentiation ISS
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010001 glial cell differentiation ISS
 biological_processGO:0021740 principal sensory nucleus of trigeminal nerve development ISS
 biological_processGO:0021960 anterior commissure morphogenesis ISS
 biological_processGO:0030324 lung development IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0030902 hindbrain development IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0060486 Clara cell differentiation ISS
 biological_processGO:0060509 type I pneumocyte differentiation ISS
 biological_processGO:0060510 type II pneumocyte differentiation ISS
 biological_processGO:0060662 salivary gland cavitation IEA
 biological_processGO:0060689 cell differentiation involved in salivary gland development IEA
 biological_processGO:0061141 lung ciliated cell differentiation ISS
 biological_processGO:0071679 commissural neuron axon guidance ISS
 biological_processGO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II IMP
 biological_processGO:2000791 negative regulation of mesenchymal cell proliferation involved in lung development ISS
 biological_processGO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis ISS
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0044300 cerebellar mossy fiber ISS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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