ENSG00000150045


Homo sapiens

Features
Gene ID: ENSG00000150045
  
Biological name :KLRF1
  
Synonyms : killer cell lectin like receptor F1 / KLRF1 / Q9NZS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.31
Gene start: 9827481
Gene end: 9845007
  
Corresponding Affymetrix probe sets: 220646_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000483713
Ensembl peptide - ENSP00000445022
Ensembl peptide - ENSP00000483880
Ensembl peptide - ENSP00000484826
Ensembl peptide - ENSP00000279545
Ensembl peptide - ENSP00000346919
Ensembl peptide - ENSP00000443054
NCBI entrez gene - 51348     See in Manteia.
OMIM - 605029
RefSeq - XM_017019414
RefSeq - NM_001291822
RefSeq - NM_001291823
RefSeq - NM_016523
RefSeq Peptide - NP_057607
RefSeq Peptide - NP_001278751
RefSeq Peptide - NP_001278752
swissprot - A0A0C4DGY9
swissprot - Q4KN30
swissprot - A0A0C4DFN7
swissprot - Q9NZS2
swissprot - Q4KMZ4
swissprot - Q4KN05
Ensembl - ENSG00000150045
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BLEC2ENSGALG00000000136Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLRF2 / D3W0D1 / killer cell lectin like receptor F2ENSG0000025679729
KLRB1 / Q12918 / killer cell lectin like receptor B1ENSG0000011179626


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR033992  Natural killer cell receptor-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0032393 MHC class I receptor activity TAS


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000110852 CLEC2B / Q92478 / C-type lectin domain family 2 member B  / complex / reaction
 ENSG00000150045 KLRF1 / Q9NZS2 / killer cell lectin like receptor F1  / complex






 

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contact: otassy@igbmc.fr