ENSG00000156298


Homo sapiens

Features
Gene ID: ENSG00000156298
  
Biological name :TSPAN7
  
Synonyms : P41732 / tetraspanin 7 / TSPAN7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: p11.4
Gene start: 38561370
Gene end: 38688920
  
Corresponding Affymetrix probe sets: 202242_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419290
Ensembl peptide - ENSP00000419321
Ensembl peptide - ENSP00000286824
Ensembl peptide - ENSP00000367743
Ensembl peptide - ENSP00000418586
NCBI entrez gene - 7102     See in Manteia.
OMIM - 300096
RefSeq - NM_004615
RefSeq Peptide - NP_004606
swissprot - F8WF47
swissprot - B4DDG0
swissprot - P41732
swissprot - F8WF53
swissprot - F8WC96
Ensembl - ENSG00000156298
  
Related genetic diseases (OMIM): 300210 - Mental retardation, X-linked 58, 300210
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tspan7bENSDARG00000008407Danio rerio
 ENSGALG00000016251Gallus gallus
 Q62283ENSMUSG00000058254Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AF241726.2ENSG0000025034991
O43657 / TSPAN6 / tetraspanin 6ENSG0000000000357
O60637 / TSPAN3 / tetraspanin 3ENSG0000014039131
Q96FV3 / TSPAN17 / tetraspanin 17ENSG0000004814029
CD63 / P08962 / CD63 moleculeENSG0000013540429
CD151 / P48509 / CD151 molecule (Raph blood group)ENSG0000017769729
Q86UF1 / TSPAN33 / tetraspanin 33ENSG0000015845728
A1L157 / TSPAN11 / tetraspanin 11ENSG0000011090027
P62079 / TSPAN5 / tetraspanin 5ENSG0000016878527
TSPAN10 / tetraspanin 10ENSG0000018261227
O95858 / TSPAN15 / tetraspanin 15ENSG0000009928225
Q8NG11 / TSPAN14 / tetraspanin 14ENSG0000010821925


Protein motifs (from Interpro)
Interpro ID Name
 IPR000301  Tetraspanin
 IPR008952  Tetraspanin, EC2 domain superfamily
 IPR018499  Tetraspanin/Peripherin
 IPR018503  Tetraspanin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway IBA
 biological_processGO:0016032 viral process IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall
Trafficking of GluR2-containing AMPA receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0001249 Mental retardation 
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 HP:0001256 Mental retardation, mild "Mild mental retardation is defined as an intelligence quotient (IQ) in the range of 50-69." [HPO:curators]
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 HP:0001417 X-linked inheritance "A mode of inheritance that is observed for traits related to a gene encoded on the X chromosome." [HPO:curators]
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 HP:0001419 X-linked recessive inheritance "A mode of inheritance that is observed for recessive traits related to a gene encoded on the X chromosome. In the context of medical genetics, X-linked recessive disorders manifest in males (who have one copy of the X chromosome and are thus hemizygotes), but generally not in female heterozygotes who have one mutant and one normal allele." [HPO:curators]
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100151 PICK1 / Q9NRD5 / protein interacting with PRKCA 1  / complex / reaction






 

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