ENSG00000160613


Homo sapiens

Features
Gene ID: ENSG00000160613
  
Biological name :PCSK7
  
Synonyms : PCSK7 / proprotein convertase subtilisin/kexin type 7 / Q16549
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q23.3
Gene start: 117204337
Gene end: 117232525
  
Corresponding Affymetrix probe sets: 203118_at (Human Genome U133 Plus 2.0 Array)   232521_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436459
Ensembl peptide - ENSP00000325917
Ensembl peptide - ENSP00000441944
Ensembl peptide - ENSP00000431181
Ensembl peptide - ENSP00000433841
Ensembl peptide - ENSP00000433252
NCBI entrez gene - 9159     See in Manteia.
OMIM - 604872
RefSeq - NM_004716
RefSeq Peptide - NP_004707
swissprot - E9PIW7
swissprot - A0A1B0GX40
swissprot - Q16549
swissprot - E9PMC0
swissprot - Q6PK65
swissprot - E9PLM0
Ensembl - ENSG00000160613
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcsk7ENSDARG00000069968Danio rerio
 PCSK7ENSGALG00000029220Gallus gallus
 Pcsk7ENSMUSG00000035382Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PCSK5 / Q92824 / proprotein convertase subtilisin/kexin type 5ENSG0000009913935
FURIN / P09958 / furin, paired basic amino acid cleaving enzymeENSG0000014056435
PCSK6 / P29122 / proprotein convertase subtilisin/kexin type 6ENSG0000014047934
PCSK1 / P29120 / proprotein convertase subtilisin/kexin type 1ENSG0000017542633
PCSK4 / Q6UW60 / proprotein convertase subtilisin/kexin type 4ENSG0000011525732
PCSK2 / P16519 / proprotein convertase subtilisin/kexin type 2ENSG0000012585128


Protein motifs (from Interpro)
Interpro ID Name
 IPR000209  Peptidase S8/S53 domain
 IPR002884  P domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR015500  Peptidase S8, subtilisin-related
 IPR022398  Peptidase S8, subtilisin, His-active site
 IPR023828  Peptidase S8, subtilisin, Ser-active site
 IPR032815  Peptidase S8, pro-domain
 IPR034182  Kexin/furin catalytic domain
 IPR036852  Peptidase S8/S53 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016485 protein processing IDA
 biological_processGO:0016486 peptide hormone processing NAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030173 integral component of Golgi membrane IDA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IDA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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