ENSG00000164889


Homo sapiens

Features
Gene ID: ENSG00000164889
  
Biological name :SLC4A2
  
Synonyms : P04920 / SLC4A2 / solute carrier family 4 member 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q36.1
Gene start: 151057210
Gene end: 151076527
  
Corresponding Affymetrix probe sets: 202111_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417221
Ensembl peptide - ENSP00000417808
Ensembl peptide - ENSP00000419412
Ensembl peptide - ENSP00000419379
Ensembl peptide - ENSP00000419164
Ensembl peptide - ENSP00000418584
Ensembl peptide - ENSP00000418114
Ensembl peptide - ENSP00000376571
Ensembl peptide - ENSP00000405600
NCBI entrez gene - 6522     See in Manteia.
OMIM - 109280
RefSeq - NM_003040
RefSeq - NM_001199692
RefSeq - NM_001199693
RefSeq - NM_001199694
RefSeq Peptide - NP_003031
RefSeq Peptide - NP_001186621
RefSeq Peptide - NP_001186622
RefSeq Peptide - NP_001186623
swissprot - P04920
swissprot - C9J9M9
swissprot - C9J722
swissprot - C9J459
swissprot - C9J035
swissprot - C9JVC2
Ensembl - ENSG00000164889
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc4a2aENSDARG00000028173Danio rerio
 slc4a2bENSDARG00000052330Danio rerio
 SLC4A2ENSGALG00000034284Gallus gallus
 Slc4a2ENSMUSG00000028962Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P48751 / SLC4A3 / solute carrier family 4 member 3ENSG0000011492358
P02730 / SLC4A1 / solute carrier family 4 member 1 (Diego blood group)ENSG0000000493944
Q9Y6M7 / SLC4A7 / solute carrier family 4 member 7ENSG0000003386732
Q9Y6R1 / SLC4A4 / solute carrier family 4 member 4ENSG0000008049332
Q6U841 / SLC4A10 / solute carrier family 4 member 10ENSG0000014429032
Q2Y0W8 / SLC4A8 / solute carrier family 4 member 8ENSG0000005043831
Q96Q91 / SLC4A9 / solute carrier family 4 member 9ENSG0000011307329
Q9BY07 / SLC4A5 / solute carrier family 4 member 5ENSG0000018868729
Q8NBS3 / SLC4A11 / solute carrier family 4 member 11ENSG0000008883618


Protein motifs (from Interpro)
Interpro ID Name
 IPR001717  Anion exchange protein
 IPR002978  Anion exchange protein 2
 IPR003020  Bicarbonate transporter, eukaryotic
 IPR011531  Bicarbonate transporter, C-terminal
 IPR013769  Band 3 cytoplasmic domain
 IPR016152  Phosphotransferase/anion transporter
 IPR018241  Anion exchange, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006820 anion transport TAS
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0015701 bicarbonate transport TAS
 biological_processGO:0048565 digestive tract development IEA
 biological_processGO:0051453 regulation of intracellular pH IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0098656 anion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0005452 inorganic anion exchanger activity TAS
 molecular_functionGO:0008509 anion transmembrane transporter activity TAS
 molecular_functionGO:0008510 sodium:bicarbonate symporter activity IBA
 molecular_functionGO:0015297 antiporter activity IEA
 molecular_functionGO:0015301 anion:anion antiporter activity IEA
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
Bicarbonate transporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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