ENSG00000188687


Homo sapiens

Features
Gene ID: ENSG00000188687
  
Biological name :SLC4A5
  
Synonyms : Q9BY07 / SLC4A5 / solute carrier family 4 member 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p13.1
Gene start: 74216242
Gene end: 74343414
  
Corresponding Affymetrix probe sets: 1555277_a_at (Human Genome U133 Plus 2.0 Array)   221723_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000377587
Ensembl peptide - ENSP00000490698
Ensembl peptide - ENSP00000490265
Ensembl peptide - ENSP00000414162
Ensembl peptide - ENSP00000407550
Ensembl peptide - ENSP00000405678
Ensembl peptide - ENSP00000399319
Ensembl peptide - ENSP00000395804
Ensembl peptide - ENSP00000251768
Ensembl peptide - ENSP00000351513
Ensembl peptide - ENSP00000366859
Ensembl peptide - ENSP00000366861
NCBI entrez gene - 57835     See in Manteia.
OMIM - 606757
RefSeq - NM_021196
RefSeq - NM_133478
RefSeq Peptide - NP_067019
RefSeq Peptide - NP_597812
swissprot - A0A1B0GUV9
swissprot - E7EQT3
swissprot - Q9BY07
swissprot - C9JW32
swissprot - C9JU12
swissprot - C9JNL6
swissprot - A0A1B0GVY3
Ensembl - ENSG00000188687
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-48m9.1ENSDARG00000002771Danio rerio
 slc4a5ENSDARG00000104387Danio rerio
 SLC4A5ENSGALG00000032146Gallus gallus
 Slc4a5ENSMUSG00000068323Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y6R1 / SLC4A4 / solute carrier family 4 member 4ENSG0000008049358
Q6U841 / SLC4A10 / solute carrier family 4 member 10ENSG0000014429046
Q9Y6M7 / SLC4A7 / solute carrier family 4 member 7ENSG0000003386745
Q2Y0W8 / SLC4A8 / solute carrier family 4 member 8ENSG0000005043844
Q96Q91 / SLC4A9 / solute carrier family 4 member 9ENSG0000011307342
P48751 / SLC4A3 / solute carrier family 4 member 3ENSG0000011492333
P04920 / SLC4A2 / solute carrier family 4 member 2ENSG0000016488932
P02730 / SLC4A1 / solute carrier family 4 member 1 (Diego blood group)ENSG0000000493929
Q8NBS3 / SLC4A11 / solute carrier family 4 member 11ENSG0000008883618


Protein motifs (from Interpro)
Interpro ID Name
 IPR003020  Bicarbonate transporter, eukaryotic
 IPR003024  Sodium bicarbonate cotransporter
 IPR011531  Bicarbonate transporter, C-terminal
 IPR013769  Band 3 cytoplasmic domain
 IPR016152  Phosphotransferase/anion transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002064 epithelial cell development IEA
 biological_processGO:0003014 renal system process IEA
 biological_processGO:0003073 regulation of systemic arterial blood pressure IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006820 anion transport IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0015701 bicarbonate transport NAS
 biological_processGO:0033326 cerebrospinal fluid secretion IEA
 biological_processGO:0048311 mitochondrion distribution IEA
 biological_processGO:0051453 regulation of intracellular pH IBA
 biological_processGO:0060041 retina development in camera-type eye IEA
 biological_processGO:0098656 anion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0005452 inorganic anion exchanger activity IEA
 molecular_functionGO:0008509 anion transmembrane transporter activity IEA
 molecular_functionGO:0008510 sodium:bicarbonate symporter activity NAS
 molecular_functionGO:0015301 anion:anion antiporter activity IEA


Pathways (from Reactome)
Pathway description
Bicarbonate transporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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