ENSG00000165389


Homo sapiens

Features
Gene ID: ENSG00000165389
  
Biological name :SPTSSA
  
Synonyms : Q969W0 / serine palmitoyltransferase small subunit A / SPTSSA
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q13.1
Gene start: 34432789
Gene end: 34462356
  
Corresponding Affymetrix probe sets: 212460_at (Human Genome U133 Plus 2.0 Array)   213508_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000298130
NCBI entrez gene - 171546     See in Manteia.
OMIM - 613540
RefSeq - NM_138288
RefSeq Peptide - NP_612145
swissprot - Q969W0
Ensembl - ENSG00000165389
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5BJC1ENSDARG00000071203Danio rerio
 SPTSSAENSGALG00000025755Gallus gallus
 Gm6993ENSMUSG00000112187Mus musculus
 Q8R207ENSMUSG00000044408Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8NFR3 / SPTSSB / serine palmitoyltransferase small subunit BENSG0000019654241


Protein motifs (from Interpro)
Interpro ID Name
 IPR024512  Small subunit of serine palmitoyltransferase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0046513 ceramide biosynthetic process IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017059 serine C-palmitoyltransferase complex IDA
 molecular_functionGO:0004758 serine C-palmitoyltransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100596 O15270 / SPTLC2 / serine palmitoyltransferase long chain base subunit 2  / complex
 ENSG00000090054 O15269 / SPTLC1 / serine palmitoyltransferase long chain base subunit 1  / complex
 ENSG00000172296 Q9NUV7 / SPTLC3 / serine palmitoyltransferase long chain base subunit 3  / complex






 

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