ENSG00000196542


Homo sapiens
serineprocessSPTSSBsphingolipidendoplasmicreticulumc-palmitoyltransferasemembranemetabolicbiosyntheticactivitysmallsubunitpalmitoyltransferase-likelipidorganizationceramideregulationintegralcomponentcomplexproteinbindingdenovobiosynthesis

Features
Gene ID: ENSG00000196542
  
Biological name :SPTSSB
  
Synonyms : Q8NFR3 / serine palmitoyltransferase small subunit B / SPTSSB
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q26.1
Gene start: 161344792
Gene end: 161372880
  
Corresponding Affymetrix probe sets: 238702_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352097
Ensembl peptide - ENSP00000420115
Ensembl peptide - ENSP00000480827
Ensembl peptide - ENSP00000483928
NCBI entrez gene - 165679     See in Manteia.
OMIM - 610412
RefSeq - XM_017005794
RefSeq - NM_001040100
RefSeq - NM_001320679
RefSeq - XM_017005793
RefSeq Peptide - NP_001035189
RefSeq Peptide - NP_001307608
swissprot - Q6ZWB5
swissprot - Q8NFR3
Ensembl - ENSG00000196542
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q1RLT2ENSDARG00000091658Danio rerio
 ENSGALG00000026131Gallus gallus
 SPTSSBENSGALG00000027494Gallus gallus
 Q925E8ENSMUSG00000043461Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q969W0 / SPTSSA / serine palmitoyltransferase small subunit AENSG0000016538938


Protein motifs (from Interpro)
Interpro ID Name
 IPR024512  Small subunit of serine palmitoyltransferase-like


Gene Ontology (GO)
primary metabolic processorganic substance metabolic processnitrogen compound metabolic processcellular metabolic processcellular component organizationbiosynthetic processregulation of molecular functionprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processcellular metabolic processcellular component organizationbiosynthetic processregulation of molecular functionprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processcellular metabolic processcellular component organizationbiosynthetic processregulation of molecular functionprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processcellular metabolic processcellular component organizationbiosynthetic processregulation of molecular functionprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processcellular metabolic processcellular component organizationbiosynthetic processregulation of molecular functionprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processcellular metabolic processcellular component organizationbiosynthetic processregulation of molecular functionprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processcellular metabolic processcellular component organizationbiosynthetic processregulation of molecular functionprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processcellular metabolic processcellular component organizationbiosynthetic processregulation of molecular functionprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processcellular metabolic processcellular component organizationbiosynthetic processregulation of molecular functionprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processcellular metabolic processcellular component organizationbiosynthetic processregulation of molecular functionprimary metabolic prprimary metabolic processorganic substance meorganic substance metabolic processnitrogen compound menitrogen compound metabolic processcellular metabolic pcellular metabolic processcellular component ocellular component organizationbiosynthetic processbiosynthetic processregulation of molecuregulation of molecular function
transferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activitytransferase activityprotein bindingprotein binding
cellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellcellorganelleorganellemembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0007029 endoplasmic reticulum organization IEA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0046513 ceramide biosynthetic process IEA
 biological_processGO:1904220 regulation of serine C-palmitoyltransferase activity IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017059 serine C-palmitoyltransferase complex IDA
 molecular_functionGO:0004758 serine C-palmitoyltransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100596 O15270 / SPTLC2 / serine palmitoyltransferase long chain base subunit 2  / complex
 ENSG00000090054 O15269 / SPTLC1 / serine palmitoyltransferase long chain base subunit 1  / complex
 ENSG00000172296 Q9NUV7 / SPTLC3 / serine palmitoyltransferase long chain base subunit 3  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr