ENSG00000167755


Homo sapiens

Features
Gene ID: ENSG00000167755
  
Biological name :KLK6
  
Synonyms : kallikrein related peptidase 6 / KLK6 / Q92876
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.41
Gene start: 50958631
Gene end: 50969673
  
Corresponding Affymetrix probe sets: 204733_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000470482
Ensembl peptide - ENSP00000469702
Ensembl peptide - ENSP00000471948
Ensembl peptide - ENSP00000309148
Ensembl peptide - ENSP00000366047
Ensembl peptide - ENSP00000375684
Ensembl peptide - ENSP00000469630
NCBI entrez gene - 5653     See in Manteia.
OMIM - 602652
RefSeq - NM_001012964
RefSeq - NM_001012965
RefSeq - NM_001319948
RefSeq - NM_001319949
RefSeq - NM_002774
RefSeq Peptide - NP_002765
RefSeq Peptide - NP_001012983
RefSeq Peptide - NP_001306877
RefSeq Peptide - NP_001306878
RefSeq Peptide - NP_001012982
swissprot - Q92876
swissprot - M0QYA5
swissprot - A0A024R4J8
Ensembl - ENSG00000167755
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Klk6ENSMUSG00000050063Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLK13 / Q9UKR3 / kallikrein related peptidase 13ENSG0000016775949
KLK14 / Q9P0G3 / kallikrein related peptidase 14ENSG0000012943746
KLK15 / Q9H2R5 / kallikrein related peptidase 15ENSG0000017456246
KLK8 / O60259 / kallikrein related peptidase 8ENSG0000012945545
KLK11 / Q9UBX7 / kallikrein related peptidase 11ENSG0000016775744
PRSS1 / P07477 / serine protease 1ENSG0000020498343
KLK9 / Q9UKQ9 / kallikrein related peptidase 9ENSG0000021302243
AC011473.4ENSG0000026974143
PRSS2 / P07478 / serine protease 2ENSG0000027589642
PRSS3 / P35030 / serine protease 3ENSG0000001043841


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007417 central nervous system development NAS
 biological_processGO:0009611 response to wounding NAS
 biological_processGO:0010975 regulation of neuron projection development IEA
 biological_processGO:0016540 protein autoprocessing NAS
 biological_processGO:0030574 collagen catabolic process NAS
 biological_processGO:0042246 tissue regeneration NAS
 biological_processGO:0042445 hormone metabolic process NAS
 biological_processGO:0042552 myelination NAS
 biological_processGO:0042982 amyloid precursor protein metabolic process NAS
 biological_processGO:0045595 regulation of cell differentiation NAS
 biological_processGO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway IDA
 biological_processGO:0070997 neuron death IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0030141 secretory granule IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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