ENSG00000169136


Homo sapiens

Features
Gene ID: ENSG00000169136
  
Biological name :ATF5
  
Synonyms : activating transcription factor 5 / ATF5 / Q9Y2D1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.33
Gene start: 49928702
Gene end: 49933935
  
Corresponding Affymetrix probe sets: 204998_s_at (Human Genome U133 Plus 2.0 Array)   204999_s_at (Human Genome U133 Plus 2.0 Array)   217389_s_at (Human Genome U133 Plus 2.0 Array)   230938_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000396954
Ensembl peptide - ENSP00000470633
Ensembl peptide - ENSP00000470978
Ensembl peptide - ENSP00000471162
Ensembl peptide - ENSP00000470464
NCBI entrez gene - 22809     See in Manteia.
OMIM - 606398
RefSeq - XM_011526629
RefSeq - NM_001193646
RefSeq - NM_001290746
RefSeq - NM_012068
RefSeq Peptide - NP_036200
RefSeq Peptide - NP_001180575
RefSeq Peptide - NP_001277675
swissprot - M0R040
swissprot - M0R0D5
swissprot - M0QZD2
swissprot - Q9Y2D1
swissprot - A0A024QZG3
Ensembl - ENSG00000169136
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atf5aENSDARG00000068096Danio rerio
 atf5bENSDARG00000077785Danio rerio
 Atf5ENSMUSG00000038539Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATF4 / P18848 / activating transcription factor 4ENSG0000012827230


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR029855  cAMP-dependent transcription factor ATF-5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0021889 olfactory bulb interneuron differentiation IEA
 biological_processGO:0021891 olfactory bulb interneuron development IEA
 biological_processGO:0021930 cerebellar granule cell precursor proliferation ISS
 biological_processGO:0021988 olfactory lobe development IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0045444 fat cell differentiation IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046605 regulation of centrosome cycle IDA
 biological_processGO:1902750 negative regulation of cell cycle G2/M phase transition IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IC
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015631 tubulin binding IDA
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding ISS
 molecular_functionGO:0044212 transcription regulatory region DNA binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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