ENSG00000169914


Homo sapiens

Features
Gene ID: ENSG00000169914
  
Biological name :OTUD3
  
Synonyms : OTUD3 / OTU deubiquitinase 3 / Q5T2D3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.13
Gene start: 19882513
Gene end: 19912945
  
Corresponding Affymetrix probe sets: 213216_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364261
NCBI entrez gene - 23252     See in Manteia.
OMIM - 611758
RefSeq - XM_005245794
RefSeq - NM_015207
RefSeq - XM_005245792
RefSeq - XM_005245793
RefSeq Peptide - NP_056022
swissprot - Q5T2D3
Ensembl - ENSG00000169914
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 otud3ENSDARG00000022648Danio rerio
 OTUD3ENSGALG00000043920Gallus gallus
 Otud3ENSMUSG00000041161Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003323  OTU domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0035871 protein K11-linked deubiquitination IDA
 biological_processGO:0044313 protein K6-linked deubiquitination IDA
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:0051898 negative regulation of protein kinase B signaling IMP
 biological_processGO:0071108 protein K48-linked deubiquitination IDA
 biological_processGO:1990167 protein K27-linked deubiquitination IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity TAS


Pathways (from Reactome)
Pathway description
Ovarian tumor domain proteases
Regulation of PTEN stability and activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000171862 PTEN / P60484 / phosphatase and tensin homolog  / reaction






 

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