ENSG00000172061


Homo sapiens

Features
Gene ID: ENSG00000172061
  
Biological name :LRRC15
  
Synonyms : leucine rich repeat containing 15 / LRRC15 / Q8TF66
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q29
Gene start: 194355247
Gene end: 194369743
  
Corresponding Affymetrix probe sets: 1552960_at (Human Genome U133 Plus 2.0 Array)   213909_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000306276
Ensembl peptide - ENSP00000413707
NCBI entrez gene - 131578     See in Manteia.
RefSeq - NM_130830
RefSeq - NM_001135057
RefSeq Peptide - NP_001128529
RefSeq Peptide - NP_570843
swissprot - Q8TF66
Ensembl - ENSG00000172061
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrc15ENSDARG00000070792Danio rerio
 LRRC15ENSGALG00000046461Gallus gallus
 Lrrc15ENSMUSG00000052316Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GP5 / P40197 / glycoprotein V plateletENSG0000017873229
CPN2 / P22792 / carboxypeptidase N subunit 2ENSG0000017877227
CHADL / Q6NUI6 / chondroadherin likeENSG0000010039926
IGFALS / P35858 / insulin like growth factor binding protein acid labile subunitENSG0000009976925
TRIL / Q7L0X0 / TLR4 interactor with leucine rich repeatsENSG0000025569025
LRRC70 / Q7Z2Q7 / leucine rich repeat containing 70ENSG0000018610522
NYX / Q9GZU5 / nyctalopinENSG0000018893721
LRRTM4 / Q86VH4 / leucine rich repeat transmembrane neuronal 4ENSG0000017620419
LRRTM2 / O43300 / leucine rich repeat transmembrane neuronal 2ENSG0000014600618
LRRTM3 / Q86VH5 / leucine rich repeat transmembrane neuronal 3ENSG0000019873918
LRRTM1 / Q86UE6 / leucine rich repeat transmembrane neuronal 1ENSG0000016295116
CHAD / O15335 / chondroadherinENSG0000013645715


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0046813 receptor-mediated virion attachment to host cell IMP
 biological_processGO:1903077 negative regulation of protein localization to plasma membrane IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001968 fibronectin binding IDA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005518 collagen binding IDA
 molecular_functionGO:0043236 laminin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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