ENSG00000176204


Homo sapiens

Features
Gene ID: ENSG00000176204
  
Biological name :LRRTM4
  
Synonyms : leucine rich repeat transmembrane neuronal 4 / LRRTM4 / Q86VH4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p12
Gene start: 76747719
Gene end: 77593319
  
Corresponding Affymetrix probe sets: 220345_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387228
Ensembl peptide - ENSP00000386357
Ensembl peptide - ENSP00000387297
Ensembl peptide - ENSP00000408722
Ensembl peptide - ENSP00000386236
Ensembl peptide - ENSP00000386286
NCBI entrez gene - 80059     See in Manteia.
OMIM - 610870
RefSeq - XM_011533117
RefSeq - NM_001134745
RefSeq - NM_001282924
RefSeq - NM_001282928
RefSeq - NM_001330370
RefSeq - NM_024993
RefSeq Peptide - NP_001317299
RefSeq Peptide - NP_079269
RefSeq Peptide - NP_001269853
RefSeq Peptide - NP_001269857
RefSeq Peptide - NP_001128217
swissprot - Q86VH4
swissprot - C9JM64
swissprot - Q4KMX1
swissprot - B8ZZ84
Ensembl - ENSG00000176204
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01102147.1ENSDARG00000106522Danio rerio
 lrrtm4l1ENSDARG00000080015Danio rerio
 lrrtm4l2ENSDARG00000099386Danio rerio
 si:dkey-28o19.1ENSDARG00000078839Danio rerio
 LRRTM4ENSGALG00000000476Gallus gallus
 Lrrtm4ENSMUSG00000052581Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRTM3 / Q86VH5 / leucine rich repeat transmembrane neuronal 3ENSG0000019873959
LRRTM1 / Q86UE6 / leucine rich repeat transmembrane neuronal 1ENSG0000016295140
LRRTM2 / O43300 / leucine rich repeat transmembrane neuronal 2ENSG0000014600638
TRIL / Q7L0X0 / TLR4 interactor with leucine rich repeatsENSG0000025569021
LRRC15 / Q8TF66 / leucine rich repeat containing 15ENSG0000017206119
GP5 / P40197 / glycoprotein V plateletENSG0000017873219
LRRC70 / Q7Z2Q7 / leucine rich repeat containing 70ENSG0000018610519
CHADL / Q6NUI6 / chondroadherin likeENSG0000010039918
CPN2 / P22792 / carboxypeptidase N subunit 2ENSG0000017877218
IGFALS / P35858 / insulin like growth factor binding protein acid labile subunitENSG0000009976917
NYX / Q9GZU5 / nyctalopinENSG0000018893716
CHAD / O15335 / chondroadherinENSG000001364578


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0050808 synapse organization IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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