ENSG00000173338


Homo sapiens

Features
Gene ID: ENSG00000173338
  
Biological name :KCNK7
  
Synonyms : KCNK7 / potassium two pore domain channel subfamily K member 7 / Q9Y2U2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.1
Gene start: 65592855
Gene end: 65595996
  
Corresponding Affymetrix probe sets: 220412_x_at (Human Genome U133 Plus 2.0 Array)   224008_s_at (Human Genome U133 Plus 2.0 Array)   224055_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431950
Ensembl peptide - ENSP00000343923
Ensembl peptide - ENSP00000377764
Ensembl peptide - ENSP00000377765
Ensembl peptide - ENSP00000435449
Ensembl peptide - ENSP00000344820
NCBI entrez gene - 10089     See in Manteia.
OMIM - 603940
RefSeq - NM_033455
RefSeq - NM_005714
RefSeq - NM_033347
RefSeq - NM_033348
RefSeq Peptide - NP_005705
RefSeq Peptide - NP_258416
RefSeq Peptide - NP_203134
RefSeq Peptide - NP_203133
swissprot - Q9Y2U2
swissprot - A0A024R5B0
swissprot - A0A024R5F5
swissprot - H0YCM4
swissprot - H0YEB9
Ensembl - ENSG00000173338
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnk7ENSDARG00000057331Danio rerio
 Kcnk7ENSMUSG00000024936Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNK1 / O00180 / potassium two pore domain channel subfamily K member 1ENSG0000013575039
KCNK6 / Q9Y257 / potassium two pore domain channel subfamily K member 6ENSG0000009933733
KCNK10 / P57789 / potassium two pore domain channel subfamily K member 10ENSG0000010043326
KCNK4 / Q9NYG8 / potassium two pore domain channel subfamily K member 4ENSG0000018245026
KCNK2 / O95069 / potassium two pore domain channel subfamily K member 2ENSG0000008248224
KCNK16 / Q96T55 / potassium two pore domain channel subfamily K member 16ENSG0000009598123
KCNK15 / Q9H427 / potassium two pore domain channel subfamily K member 15ENSG0000012424923
KCNK5 / O95279 / potassium two pore domain channel subfamily K member 5ENSG0000016462622
KCNK9 / Q9NPC2 / potassium two pore domain channel subfamily K member 9ENSG0000016942722
KCNK17 / Q96T54 / potassium two pore domain channel subfamily K member 17ENSG0000012478021
KCNK3 / O14649 / potassium two pore domain channel subfamily K member 3ENSG0000017130321


Protein motifs (from Interpro)
Interpro ID Name
 IPR003092  Two pore domain potassium channel, TASK family
 IPR003280  Two pore domain potassium channel
 IPR005408  Two pore domain potassium channel, TWIK family
 IPR013099  Potassium channel domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport TAS
 biological_processGO:0030322 stabilization of membrane potential IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005267 potassium channel activity TAS
 molecular_functionGO:0022841 potassium ion leak channel activity IBA


Pathways (from Reactome)
Pathway description
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)
Phase 4 - resting membrane potential


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000173338 KCNK7 / Q9Y2U2 / potassium two pore domain channel subfamily K member 7  / complex






 

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