ENSG00000176490


Homo sapiens

Features
Gene ID: ENSG00000176490
  
Biological name :DIRAS1
  
Synonyms : DIRAS1 / DIRAS family GTPase 1 / O95057
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 2714567
Gene end: 2721418
  
Corresponding Affymetrix probe sets: 226573_at (Human Genome U133 Plus 2.0 Array)   232854_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000325836
Ensembl peptide - ENSP00000466733
Ensembl peptide - ENSP00000468417
NCBI entrez gene - 148252     See in Manteia.
OMIM - 607862
RefSeq - XM_011527713
RefSeq - NM_145173
RefSeq Peptide - NP_660156
swissprot - O95057
swissprot - K7EN06
Ensembl - ENSG00000176490
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 diras1aENSDARG00000028066Danio rerio
 diras1bENSDARG00000009372Danio rerio
 DIRAS1ENSGALG00000026955Gallus gallus
 Diras1ENSMUSG00000043670Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DIRAS2 / Q96HU8 / DIRAS family GTPase 2ENSG0000016502379
DIRAS3 / O95661 / DIRAS family GTPase 3ENSG0000016259546
RAP2C / Q9Y3L5 / RAP2C, member of RAS oncogene familyENSG0000012372843
RAP2A / P10114 / RAP2A, member of RAS oncogene familyENSG0000012524942
RAP2B / P61225 / RAP2B, member of RAS oncogene familyENSG0000018146741
RASD2 / Q96D21 / RASD family member 2ENSG0000010030240
RASD1 / Q9Y272 / ras related dexamethasone induced 1ENSG0000010855138
RAP1A / P62834 / RAP1A, member of RAS oncogene familyENSG0000011647338
RAP1B / P61224 / RAP1B, member of RAS oncogene familyENSG0000012731438
RIT2 / Q99578 / Ras like without CAAX 2ENSG0000015221436
RIT1 / Q92963 / Ras like without CAAX 1ENSG0000014362233
Q92737 / RASL10A / RAS like family 10 member AENSG0000010027628
Q96S79 / RASL10B / RAS like family 10 member BENSG0000027088528


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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