ENSG00000176871


Homo sapiens
domainwdWSB2repeatsuperfamilyproteinsocs-repeat-containingintracellularboxsix-bladedbeta-propellertolb-likeyvtnrepeat-like-containingconservedsiteg-proteinbetawd-box-likeubiquitinationsignaltransductionpost-translationalmodificationcytosolbindingneddylation

Features
Gene ID: ENSG00000176871
  
Biological name :WSB2
  
Synonyms : Q9NYS7 / WD repeat and SOCS box containing 2 / WSB2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.23
Gene start: 118032694
Gene end: 118062430
  
Corresponding Affymetrix probe sets: 201760_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445547
Ensembl peptide - ENSP00000319474
Ensembl peptide - ENSP00000409131
Ensembl peptide - ENSP00000438433
Ensembl peptide - ENSP00000439450
Ensembl peptide - ENSP00000440386
Ensembl peptide - ENSP00000444431
NCBI entrez gene - 55884     See in Manteia.
RefSeq - XM_017019642
RefSeq - NM_001278557
RefSeq - NM_001278558
RefSeq - NM_018639
RefSeq Peptide - NP_061109
RefSeq Peptide - NP_001265486
RefSeq Peptide - NP_001265487
swissprot - F5H280
swissprot - F5H2L7
swissprot - F5H024
swissprot - Q9NYS7
swissprot - F5GXB6
Ensembl - ENSG00000176871
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wsb2ENSDARG00000058608Danio rerio
 WSB2ENSGALG00000008151Gallus gallus
 Wsb2ENSMUSG00000029364Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WSB1 / Q9Y6I7 / WD repeat and SOCS box containing 1ENSG0000010904647
CIAO1 / O76071 / cytosolic iron-sulfur assembly component 1ENSG0000014402119


Protein motifs (from Interpro)
Interpro ID Name
 IPR001496  SOCS box domain
 IPR001680  WD40 repeat
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036036  SOCS box-like domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabnitrogen compound metabolic processcellular metabolic proccellular metabolic processprimary metabolic proceprimary metabolic processorganic substance metaborganic substance metabolic processcell communicationcell communicationcellular response to stcellular response to stimulus
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellcellcellcellcellcellcellcellcellcellcellcell
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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