ENSG00000177669


Homo sapiens

Features
Gene ID: ENSG00000177669
  
Biological name :MBOAT4
  
Synonyms : MBOAT4 / membrane bound O-acyltransferase domain containing 4 / Q96T53
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: p12
Gene start: 30131824
Gene end: 30144686
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000314196
NCBI entrez gene - 619373     See in Manteia.
OMIM - 611940
RefSeq - NM_001100916
RefSeq - XM_017013726
RefSeq Peptide - NP_001094386
swissprot - Q96T53
Ensembl - ENSG00000177669
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mboat4ENSDARG00000052110Danio rerio
 MBOAT4ENSGALG00000011454Gallus gallus
 Mboat4ENSMUSG00000071113Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MBOAT2 / Q6ZWT7 / membrane bound O-acyltransferase domain containing 2ENSG0000014379721
MBOAT1 / Q6ZNC8 / membrane bound O-acyltransferase domain containing 1ENSG0000017219721
LPCAT3 / Q6P1A2 / lysophosphatidylcholine acyltransferase 3ENSG0000011168417
MBOAT7 / Q96N66 / membrane bound O-acyltransferase domain containing 7ENSG0000012550516


Protein motifs (from Interpro)
Interpro ID Name
 IPR004299  Membrane bound O-acyl transferase, MBOAT


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0018191 peptidyl-serine octanoylation IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 molecular_functionGO:0008374 O-acyltransferase activity TAS
 molecular_functionGO:0016412 serine O-acyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA


Pathways (from Reactome)
Pathway description
Synthesis, secretion, and deacylation of Ghrelin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000157017 GHRL / Q9UBU3 / ghrelin and obestatin prepropeptide  / reaction






 

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