ENSG00000177674


Homo sapiens
membraneAGTRAPangiotensiniiproteinsignalinggolgiendoplasmicreticulumcytoplasmicvesicletype-receptor-associatedresponsehypoxiaregulationbloodpressureangiotensin-activatedpathwaynucleoplasmapparatuscytosolplasmacellcortexintegralcomponentintracellularmembrane-boundedorganelle

Features
Gene ID: ENSG00000177674
  
Biological name :AGTRAP
  
Synonyms : AGTRAP / angiotensin II receptor associated protein / Q6RW13
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.22
Gene start: 11736084
Gene end: 11754802
  
Corresponding Affymetrix probe sets: 1555736_a_at (Human Genome U133 Plus 2.0 Array)   225059_at (Human Genome U133 Plus 2.0 Array)   238135_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000408505
Ensembl peptide - ENSP00000383688
Ensembl peptide - ENSP00000422647
Ensembl peptide - ENSP00000424455
Ensembl peptide - ENSP00000319713
Ensembl peptide - ENSP00000365814
Ensembl peptide - ENSP00000365816
Ensembl peptide - ENSP00000365824
NCBI entrez gene - 57085     See in Manteia.
OMIM - 608729
RefSeq - XM_011541802
RefSeq - NM_001040194
RefSeq - NM_001040195
RefSeq - NM_001040196
RefSeq - NM_001040197
RefSeq - NM_020350
RefSeq - XM_011541799
RefSeq - XM_011541800
RefSeq Peptide - NP_001035284
RefSeq Peptide - NP_001035286
RefSeq Peptide - NP_001035287
RefSeq Peptide - NP_065083
RefSeq Peptide - NP_001035285
swissprot - Q6RW13
swissprot - D6RBK6
swissprot - X6R9H3
swissprot - D6RB40
Ensembl - ENSG00000177674
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agtrapENSDARG00000077082Danio rerio
 AGTRAPENSGALG00000004623Gallus gallus
 AgtrapENSMUSG00000029007Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009436  Type-1 angiotensin II receptor-associated protein


Gene Ontology (GO)
response to stressresponse to abiotic stimulusregulation of biological qualitysystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusresponse to stressresponse to abiotic stimulusregulation of biological qualitysystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusresponse to stressresponse to abiotic stimulusregulation of biological qualitysystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusresponse to stressresponse to abiotic stimulusregulation of biological qualitysystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusresponse to stressresponse to abiotic stimulusregulation of biological qualitysystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusresponse to stressresponse to abiotic stimulusregulation of biological qualitysystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusresponse to stressresponse to abiotic stimulusregulation of biological qualitysystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusresponse to stressresponse to abiotic stimulusregulation of biological qualitysystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusresponse to stressresponse to abiotic stimulusregulation of biological qualitysystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusresponse to stressresponse to abiotic stimulusregulation of biological qualitysystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusresponse to stresresponse to stressresponse to abiotresponse to abiotic stimulusregulation of bioregulation of biological qualitysystem processsystem processcell communicatiocell communicationresponse to endogresponse to endogenous stimulusresponse to chemiresponse to chemicalcellular responsecellular response to stimulus
signaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activitysignaling receptor activityprotein bindingprotein binding
cellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellcellmembranemembraneorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0038166 angiotensin-activated signaling pathway IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004945 angiotensin type II receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Signaling by BRAF and RAF fusions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000177674 AGTRAP / Q6RW13 / angiotensin II receptor associated protein  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr