ENSG00000178913


Homo sapiens

Features
Gene ID: ENSG00000178913
  
Biological name :TAF7
  
Synonyms : Q15545 / TAF7 / TATA-box binding protein associated factor 7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q31.3
Gene start: 141260225
Gene end: 141320821
  
Corresponding Affymetrix probe sets: 201023_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000312709
Ensembl peptide - ENSP00000485510
NCBI entrez gene - 6879     See in Manteia.
OMIM - 600573
RefSeq - NM_005642
RefSeq Peptide - NP_005633
swissprot - A0A096LPC3
swissprot - Q15545
Ensembl - ENSG00000178913
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taf7ENSDARG00000019572Danio rerio
 TAF7ENSGALG00000004999Gallus gallus
 Taf7ENSMUSG00000051316Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TAF7L / Q5H9L4 / TATA-box binding protein associated factor 7 likeENSG0000010238759


Protein motifs (from Interpro)
Interpro ID Name
 IPR006751  TAFII55 protein, conserved region


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0000296 spermine transport ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006352 DNA-templated transcription, initiation IDA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0006469 negative regulation of protein kinase activity IDA
 biological_processGO:0030520 intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0035067 negative regulation of histone acetylation IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0051123 RNA polymerase II transcriptional preinitiation complex assembly IBA
 biological_processGO:0060260 regulation of transcription initiation from RNA polymerase II promoter NAS
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IPI
 cellular_componentGO:0005669 transcription factor TFIID complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0008024 cyclin/CDK positive transcription elongation factor complex IDA
 cellular_componentGO:0033276 transcription factor TFTC complex IDA
 cellular_componentGO:0071339 MLL1 complex IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0035035 histone acetyltransferase binding IEA
 molecular_functionGO:0042809 vitamin D receptor binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046966 thyroid hormone receptor binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0061628 H3K27me3 modified histone binding IPI


Pathways (from Reactome)
Pathway description
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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