ENSG00000180233


Homo sapiens

Features
Gene ID: ENSG00000180233
  
Biological name :ZNRF2
  
Synonyms : Q8NHG8 / zinc and ring finger 2 / ZNRF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p14.3
Gene start: 30284307
Gene end: 30367692
  
Corresponding Affymetrix probe sets: 226261_at (Human Genome U133 Plus 2.0 Array)   229188_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000323879
NCBI entrez gene - 223082     See in Manteia.
OMIM - 612061
RefSeq - NM_147128
RefSeq Peptide - NP_667339
swissprot - A0A090N8Y8
swissprot - Q8NHG8
Ensembl - ENSG00000180233
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q08CN9ENSDARG00000098792Danio rerio
 ZNRF2ENSGALG00000031163Gallus gallus
 Znrf2ENSMUSG00000058446Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZNRF1 / Q8ND25 / zinc and ring finger 1ENSG0000018618739


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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