ENSG00000181773


Homo sapiens
receptorGPR3membranegprotein-coupledg-proteincoupledrhodopsin-likesignalsignalingpathwayplasmaintegralcomponentactivityorphangpcrtmtransductionadenylatecyclase-activatingregulationmeioticnucleardivisionintracellularobsoletetransducerproteinbinding

Features
Gene ID: ENSG00000181773
  
Biological name :GPR3
  
Synonyms : GPR3 / G protein-coupled receptor 3 / P46089
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.11
Gene start: 27392644
Gene end: 27395814
  
Corresponding Affymetrix probe sets: 214613_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000363136
NCBI entrez gene - 2827     See in Manteia.
OMIM - 600241
RefSeq - NM_005281
RefSeq Peptide - NP_005272
swissprot - F1DAM5
swissprot - P46089
Ensembl - ENSG00000181773
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Gpr3ENSMUSG00000049649Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPR6 / P46095 / G protein-coupled receptor 6ENSG0000014636059
GPR12 / P47775 / G protein-coupled receptor 12ENSG0000013297556
S1PR5 / Q9H228 / sphingosine-1-phosphate receptor 5ENSG0000018073931
LPAR2 / Q9HBW0 / lysophosphatidic acid receptor 2ENSG0000006454728
LPAR3 / Q9UBY5 / lysophosphatidic acid receptor 3ENSG0000017151725
S1PR3 / Q99500 / sphingosine-1-phosphate receptor 3ENSG0000021369425
S1PR2 / O95136 / sphingosine-1-phosphate receptor 2ENSG0000026753425
S1PR4 / O95977 / sphingosine-1-phosphate receptor 4ENSG0000012591024
S1PR1 / P21453 / sphingosine-1-phosphate receptor 1ENSG0000017098924
LPAR1 / Q92633 / lysophosphatidic acid receptor 1ENSG0000019812124
CNR1 / P21554 / cannabinoid receptor 1ENSG0000011843223
CNR2 / P34972 / cannabinoid receptor 2ENSG0000018882221


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000723  G protein-coupled receptor 3/6/12 orphan
 IPR000984  G protein-coupled receptor 3
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
cell communicationcellular response to stimuluscellular component organizationcell cyclecell communicationcellular response to stimuluscellular component organizationcell cyclecell communicationcellular response to stimuluscellular component organizationcell cyclecell communicationcellular response to stimuluscellular component organizationcell cyclecell communicationcellular response to stimuluscellular component organizationcell cyclecell communicationcellular response to stimuluscellular component organizationcell cyclecell communicationcellular response to stimuluscellular component organizationcell cyclecell communicationcellular response to stimuluscellular component organizationcell cyclecell communicationcellular response to stimuluscellular component organizationcell cyclecell communicationcellular response to stimuluscellular component organizationcell cyclecell communicationcell communicationcellular response to stimuluscellular response to stimuluscellular component organizationcellular component organizationcell cyclecell cycle
signaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activitysignaling receptor activityprotein bindingprotein binding
cellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0040020 regulation of meiotic nuclear division IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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