ENSG00000188822


Homo sapiens

Features
Gene ID: ENSG00000188822
  
Biological name :CNR2
  
Synonyms : cannabinoid receptor 2 / CNR2 / P34972
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.11
Gene start: 23870526
Gene end: 23913362
  
Corresponding Affymetrix probe sets: 206586_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000363596
NCBI entrez gene - 1269     See in Manteia.
OMIM - 605051
RefSeq - XM_017000261
RefSeq - NM_001841
RefSeq - XM_011540629
RefSeq Peptide - NP_001832
swissprot - P34972
swissprot - A0A024RAH7
Ensembl - ENSG00000188822
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cnr2ENSDARG00000039970Danio rerio
 CNR2ENSGALG00000004120Gallus gallus
 Cnr2ENSMUSG00000062585Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CNR1 / P21554 / cannabinoid receptor 1ENSG0000011843242
S1PR4 / O95977 / sphingosine-1-phosphate receptor 4ENSG0000012591023
S1PR1 / P21453 / sphingosine-1-phosphate receptor 1ENSG0000017098923
S1PR5 / Q9H228 / sphingosine-1-phosphate receptor 5ENSG0000018073923
LPAR2 / Q9HBW0 / lysophosphatidic acid receptor 2ENSG0000006454722
LPAR1 / Q92633 / lysophosphatidic acid receptor 1ENSG0000019812122
S1PR3 / Q99500 / sphingosine-1-phosphate receptor 3ENSG0000021369422
GPR12 / P47775 / G protein-coupled receptor 12ENSG0000013297521
GPR6 / P46095 / G protein-coupled receptor 6ENSG0000014636021
S1PR2 / O95136 / sphingosine-1-phosphate receptor 2ENSG0000026753421
LPAR3 / Q9UBY5 / lysophosphatidic acid receptor 3ENSG0000017151719
GPR3 / P46089 / G protein-coupled receptor 3ENSG0000018177319


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001551  Cannabinoid receptor type 2
 IPR002230  Cannabinoid receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001975 response to amphetamine IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0030595 leukocyte chemotaxis IEA
 biological_processGO:0032229 negative regulation of synaptic transmission, GABAergic IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0033004 negative regulation of mast cell activation IEA
 biological_processGO:0038171 cannabinoid signaling pathway IEA
 biological_processGO:0045759 negative regulation of action potential IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0051001 negative regulation of nitric-oxide synthase activity IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004949 cannabinoid receptor activity TAS


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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